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What are the side effects and contraindications of targeted drugs

What are the side effects and contraindications of targeted drugs

2026-09-30 03:43
1 answer

The side effects of the targeted drug were as follows: - The most common side effects were diarrhea (47%), oral cavity inflammation (24%), rash (46%), paronychus (34%), dry skin (32%), itching (17%), white blood cell reduction (65%), splenopenias (64%), plateletlessness (53%), and neutropenias (36%). - The common side effects were: interstitial pneumonias, hair loss, hives, palmar-toe redness and swelling syndrome, increased blood creatine-Phosphoprotein Kinase, increased blood creatinic acid, and prolonged QT-interval. - Occasionally, the side effects included keratis, vasculitides, erythema multiforma, and toxic epicutaneous necrolysis. - Other side effects: acne, liver damage, dry skin, cracked hands and feet, eye disease, bone marrow suppression, respiratory system damage, liver and kidney function damage, nerve damage, digestive system damage, metabolism system damage, skeletal system damage, poor appetite, vomiting, constipation, oxygen deficiency, decreased immunity, weak blood coagulation function, cough, difficulty breathing, icterus, edema, fatigue, anesthesia, hypoproteinuria, body swelling, etc. The contraindications of targeted drugs were as follows: - To avoid adjusting the dosage without authorization: The patient needs to take the targeted drug under the guidance of the doctor, strictly abide by the time and dosage of the drug, and take the drug on time and in the right amount. This is conducive to maintaining the blood concentration of the drug in the blood and avoid increasing or reducing the dosage without authorization. - Avoiding foods that inhibit the activity of the CyP3A4: Since the targeted drug is digested by the CyP3A4, you should avoid eating foods that inhibit the activity of the CyP3A4, such as star fruit, pomegranate, and grapefruit. - Avoidance of drugs that induce the production of CyP3A4: During the period of taking targeted drugs, patients should avoid taking drugs that induce the production of CyP3A4, such as carbamazepin and rifampicin, to avoid excessive levels of CyP3A4 in the body and shorten the time the drug stays in the body. Read more exciting novels for free

She is the Side Character! — Watch Her Change her fate!

She is the Side Character! — Watch Her Change her fate!

997 signed a contract with a newbie host named Ah Chen, and even coaxed (strikethrough) them into a permanent bind. Soon, it was discovered that the seemingly obedient and honest new host had two faces. The 1st World: She transmigrated into a Princely Heir disguised as a man, with her father, a different-surnamed king, about to rebel. In the end, their family failed and was annihilated. At the critical moment, Ah Chen decisively knocked her father unconscious with a karate chop. Rebellion? Not possible. To prevent her father from causing trouble and implicating the family, she brewed a delicious mushroom soup, allowing him to spend the rest of his life capturing small men to pass the time. The Emperor: I heard someone was rebelling. I set up an inescapable net and waited all night. May I ask where the rebels are? The 2nd World: A big star used her resources to support a scumbag, only to be ruined by him in the end? Ah Chen stated that with her presence, there was no way the ungrateful scumbag could ever make a name for himself. The one to lose reputation and status could only be him. The 3rd World: On the wedding night, the groom ran away, leaving behind an entire family for her to serve? Ah Chen smiled with curved brows, "Meet the fierce daughter-in-law!" …… 997 gradually accepted his fate until one day he discovered another secret of the host, and he was greatly shocked! 997: Host, you're making me feel very unfamiliar. Ah Chen: You'll get more familiar with time. 997: …… [1v1, male lead fragment, ultimate romance, some worlds might not appear due to settings]
Sci-fi
868 Chs
My Abilities Come with Special Effects

My Abilities Come with Special Effects

In the world of dynasties and martial arts, Lin Yan awakened the memories of his past life and struggled to survive with his half-sister. Fortunately, he awakened cheats. As long as the ability proficiency reached 100%, he could sublimate the skill to the extreme and give rise to strange special effects. Swallowing - [Transforming Poison]: Invulnerable to all kinds of poisons, swallowing poisons can be transformed into qi and blood to feed oneself. Five Birds Hand - [Spring Return]: consume qi and blood to recover from injuries Dragon Fist - [Cloud from Dragon]: Ride the wind to swim the dragon, and speed instantly doubled. Mountain Breaking Fist - [Wind from Tiger]: White Tiger breaks the army, and instantly doubles the instant damage. Attack - [Ape God Strike]: The whole body force converges in one point. Defense - [No Phase]: Distribute the attack received evenly to all parts of the body ... A secret realm wrapped in poisonous miasma, where no one could enter without being killed by touching it? I had [Swallowing - Transforming Poison]. I could enter and leave the secret realm at will. The secret medicine must be used to counteract the injury? I had [Five Birds Hand - Spring Return], and I could practice at will without fear. Every special effect was a cheat. The world was in turmoil with demons, the people were like ghosts, the ancient world was revived, and the world would be in chaos. Only with the idea of invincibility, I should open up a path of prosperity, overlooking the nature of the rivers and mountains.
Action
644 Chs

What are the side effects of general targeted therapy drugs?

The side effects of targeted therapy mainly included the following aspects: 1. Digestive tract reactions: The targeted drug may stimulate the digestive tract, causing nausea, vomiting, diarrhea, abdominal distension, and other symptoms. This is a relatively common side effect. In addition, the combination of targeted drugs and chemotherapy may also cause a digestive reaction. 2. Liver and kidney toxicity: The drug may be digested in the liver or kidneys after blood circulation, which may increase the burden on the liver and kidney. When used in large doses, it may cause liver and kidney incompetence. 3. Fetal toxicity: Some special targeted drugs have fetal toxicity, such as trastuzumi, which easily passes through the placental barrier and may cause fetal abnormality. Pregnant women should avoid using such targeted drugs with strong fetal toxicity. 4. Others: Fever, chills, bone marrow suppression, allergy (very few patients are allergic to the targeted drug components), and other conditions may occur. In patients treated with Herceptin, symptoms and signs of decreased cardiac function may occur. During the period of taking the medicine, there may be adverse reactions such as peeling, pain, inflammation, etc. In addition, a sudden increase in dosage would cause fluctuations in blood concentration, affect the efficacy, accelerate drug resistance, and even cause serious adverse reactions. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>

1 answer
2026-07-29 22:29

What are the effects and contraindications of iodinated drugs?

The effects of the iodate include: - It is used for the prevention and treatment of local goiter. A small dose of iodine-based preparation can be used as a raw material to supply iodine-based synthesis of thyronine to correct the excessive secretion of hypophysis and reduce the size of the swollen goiter. - In the preparation for surgery for hyperthyreosis and hyperthyreosis crisis, a large dose of iodination could be used as an anti-thyreosis drug to temporarily control hyperthyreosis. It could also resist the effect of the hypophysis's thyreotroph, causing the thyreoid tissue to shrink and harden, and the blood vessels to decrease, which was beneficial for surgery. The contraindications and precautions for the use of iodate were as follows: - It should be banned in infants and young children who are allergic to disinfectant. - It should be used with caution in patients with oral diseases, acute asthma, malaria, hyperkalemia, hyperthyreosis, impaired kidney function, and women during pregnancy and breast-feeding. - After taking it, there may be allergic reactions, joint pain, digestive tract reactions, burning sensation in the mouth, peripheral distension, and other adverse reactions. Long-term use may also cause burning sensation in the mouth and throat, salivation, metallic taste, gum pain, stomach discomfort, severe headache, and other symptoms of iodinism. It should be noted that the situation of iodinated drugs was described here with the example of potassium iodate. Different iodinated drugs may have differences, and the specific use should follow the doctor's advice. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>

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2026-07-28 09:28

What are the side effects of targeted drugs for head and neck cancer?

Different types of targeted drugs had different side effects. If it was a targeted drug with a positive expression of HER - 2, the main side effect might be diarrhea. If it was combined with other chemotherapy drugs, it might also cause white blood cell and Platelet decrease, fatigue, etc.; Monocentric antibody-targeted drugs may cause side effects such as high blood pressure, proteuria, liver and kidney function abnormalities; Tyrosinase kinases that target gene mutations may cause side effects such as rash, itching, mucus membrane inflammation, oral ulcers, diarrhea, etc. In addition, targeted drugs generally may also have digestive toxicity, such as loss of appetite, nausea, abdominal distension, abdominal pain, vomiting, diarrhea, etc.; general allergic reactions such as skin itching, redness, hair loss, blackening of nails, cracks, peeling, chapped skin, and general rashes; liver toxicity such as increased body indicators such as direct Bilirubin, indirect Bilirubin, Altaic Pyrutanase, etc.; cardiovascular reactions such as increased blood pressure, proteinuria, etc., as well as damage to the skin, such as decreased skin resistance. There were pustules, itchy skin, chapped skin, abnormal nails, and hair loss. However, there was no specific description of the side effects of targeted drugs for head and neck cancer. The side effects might cover these aspects. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>

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2026-08-10 04:16

Side effects and contraindications of rabies vaccine

The side effects of the rabies vaccine mainly included headache, discomfort, nausea, local pain, redness, and induration. A small number of people may have symptoms such as itchy skin, swollen nodes, fever, physical fatigue, and vomiting. However, the degree of side effects of the rabies vaccine was related to the individual's physical fitness, and the side effects were generally mild. As for the taboo of rabies vaccine, according to the information provided, there was no absolute contraindication for rabies vaccine after exposure. However, the basic conditions of the recipient should be fully inquired before the vaccine, such as whether there is a history of severe allergy or other serious diseases. If there are conditions that are not suitable for the vaccine, it should be administered under close supervision. In general, rabies vaccine was a life-saving vaccine. Because rabies was a fatal disease, once you were scratched or bitten by an animal, you should get a rabies vaccine in time.

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2024-12-31 23:34

What are the side effects and contraindications of painkiller?

Zhentongning was a Chinese patent medicine. Its main ingredient was belladona extract, which had antipyretic and painkiller effects. The possible side effects include nausea, vomiting, dry mouth, constipation, rash, blurred vision, difficulty urinating, etc. Some patients may also have diarrhea after taking it. In terms of contraindications, Zhentongning could not be taken at the same time as Shalianhewei capsules because the two drugs had the same effect. Taking them at the same time might cause interactions between the drugs, resulting in diarrhea symptoms. It is suggested that the patient should take the painkiller under the doctor's guidance. Do not blindly use the medicine on your own. If there are adverse reactions, stop the medicine in time and consult the doctor in the hospital. Change the treatment with other drugs under the doctor's guidance. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>

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2026-07-28 16:25

What are the side effects and contraindications of valsartan?

The side effects of valsartan included cough, abdominal pain, dizziness, kidney damage, increased Creonin, hyperkalemia-induced, vasoneurotic edema, temporary headache, dizziness, fatigue, increased Blood Kalium, decreased neutrons, decreased hemoglobinand packed blood cell volume, increased Blood Creantine and Transaminases, diarrhea, nasal obstruction, inflammation, joint pain, nausea, low blood pressure, and temporary allergic reactions (such as skin itching and rash). The contraindications of valsartan are: it is contraindicated for people allergic to valsartan or any other excipient in valsartan; it is not allowed to use this product together with aliskiren in patients with diabetes; it is prohibited in pregnant and breast-feeding women; it should be used with caution in patients with severe kidney failure, double kidney artery narrowing, and hyperkalemias; it should be used with caution in patients with liver function and kidney function damage. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>

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2026-08-11 10:05

What are the side effects and contraindications of the liver-nourishing tablets?

If the liver-nourishing tablets referred to liver-protecting tablets, the side effects were as follows: 1. Long-term or inappropriate use will increase the burden on the liver and may damage liver function. For example, long-term, large amounts of drugs, or excessive use when there is no clear liver disease, as well as taking too many types, too large doses, and too long, may lead to such results, and may even cause drug-induced leukemia. 2. It may cause allergic reactions in the body, such as itchy skin, redness and swelling. In severe cases, chest tightness, difficulty breathing, and other symptoms. The taboos were: 1. People with spleen and stomach deficiency should take it with caution, because long-term or large-scale consumption may cause the condition to worsen. 2. During the period of taking medicine, you should avoid eating spicy and greasy food and avoid drinking alcohol. 3. You should avoid catching a cold, pay attention to rest, keep your stool unobstructed, and arrange your diet reasonably. It should be noted that if it is not referring to liver protection tablets, please specify the specific name of the drug so that you can answer accurately. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>

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2026-07-19 00:53

What are the side effects and contraindications of licorice heart-draining soup?

The taboos of the licorice heart-draining soup were as follows: 1. Pregnant women are forbidden to use it because the rhubarb contained in it has a laxative effect and may affect the fetus. 2. It is prohibited for people suffering from intestinal obstruction, inflammatory Bowel Disease, severe diarrhea, or dehydration. 3. Patients with digestive system diseases such as gastric and Duodenal Ulcers should be used with caution to avoid worsening the condition. 4. People with high blood pressure should use it with caution because licorice acid can increase blood pressure. 5. Children and women who are breast-feeding should not take it. 6. It is not suitable for patients with heart disease, low blood pressure, low blood sugar, and poor liver and kidney function. 7. People who are allergic to licorice, rhubarb, and other ingredients should not take it. The side effects of the licorice heart-draining soup were as follows: 1. It may cause indigestion, diarrhea, etc., and diarrhea may worsen in people with poor digestive function. 2. Long-term and high-dose use may cause hypokalemia, resulting in muscle weakness, cardiac arrest, and other symptoms. 3. Long-term consumption may cause damage to liver and kidney function. 4. Overdosage could cause problems such as high blood pressure and cardiac arrest. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>

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2026-08-01 14:22

What are the side effects of Chinese medicine wine and its contraindications

The alcoholic scutellaria root had the effects of clearing heat, drying dampness, purging fire, detoxifying, stopping bleeding, and preventing miscarriage. Its contraindication is that it is not suitable for people with deficiency and cold of the spleen and stomach, because the bitter cold of wine scutellaria can damage the yang qi of the spleen and stomach. The adverse effects of drinking scutellaria were still unclear. It is not recommended to use wine scutellaria alone for treatment. It should be used in combination with other drugs to achieve better results. It is recommended to use wine scutellaria under the guidance of a professional doctor. It is not allowed to use the medicine on its own. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>

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2026-08-02 12:54

What are the symptoms and reactions of the side effects and contraindications of Shu Chuanling?

Muscle tremors were common among the adverse reactions of salbuturon. Nausea, increased heart rate, or irregular heartbeat could also be seen. Occasionally, she would experience dizziness, dizziness, headache, dizziness, dry mouth, vexation, high blood pressure, insomnia, vomiting, flushing, and other symptoms. It should not be used together with antidepots. Athletes should use it with caution. The specific use of drugs should be carried out under the guidance of a doctor and should not be used blindly. If there were any other abnormalities, they needed to consult a doctor or go to the hospital in time. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>

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2026-08-20 15:30
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