What are the side effects of targeted drugs for head and neck cancer?
Different types of targeted drugs had different side effects. If it was a targeted drug with a positive expression of HER - 2, the main side effect might be diarrhea. If it was combined with other chemotherapy drugs, it might also cause white blood cell and Platelet decrease, fatigue, etc.; Monocentric antibody-targeted drugs may cause side effects such as high blood pressure, proteuria, liver and kidney function abnormalities; Tyrosinase kinases that target gene mutations may cause side effects such as rash, itching, mucus membrane inflammation, oral ulcers, diarrhea, etc. In addition, targeted drugs generally may also have digestive toxicity, such as loss of appetite, nausea, abdominal distension, abdominal pain, vomiting, diarrhea, etc.; general allergic reactions such as skin itching, redness, hair loss, blackening of nails, cracks, peeling, chapped skin, and general rashes; liver toxicity such as increased body indicators such as direct Bilirubin, indirect Bilirubin, Altaic Pyrutanase, etc.; cardiovascular reactions such as increased blood pressure, proteinuria, etc., as well as damage to the skin, such as decreased skin resistance. There were pustules, itchy skin, chapped skin, abnormal nails, and hair loss. However, there was no specific description of the side effects of targeted drugs for head and neck cancer. The side effects might cover these aspects. Read more exciting novels for free
What are the side effects of cancer drugs?
The side effects of cancer drugs included the following: 1. ** Skin and mucus membrane related **: - The targeted drug may cause "accidental injury" to the skin and mucus membrane due to its mechanism of action, resulting in rashes and sores. This was because there were targets similar to tumor cells in normal skin and mucus membrane. After the targeted drug combined with these targets, it would cause skin damage, produce an inflammatory reaction, and form rashes, while sores would appear in the mucus membrane. - Skin toxicity also included dry skin, hives, skin coloring, and even redness, peeling skin, etc. Some chemotherapy drugs could cause varying degrees of hair loss. 2. ** Digestive System Reaction **: - Radiation therapy and chemotherapy can cause the small intestine's hemoffin cells to release 5 - HT, which can stimulate the vagal nerves through the 5 -ht3 receptor, leading to vomiting reflex. There will also be loss of appetite, dry mouth, tooth and oral soft tissue infection, oral ulcers, oral candidiasis, digestive tract myozotis, constipation, paralytic intestinal obstruction, diarrhea, abnormal liver function, etc. In severe cases, it can lead to gastric ulcers, acute inflammation, intestinal obstruction, intestinal bleeding, and intestinal necrosis. 3. Bone marrow suppression: - The chemotherapy drugs targeted DNA synthesis and the late stage of mitosis, which broke the dynamic balance of blood cells in the body. After the old blood cells died naturally, the new blood cells were not born enough due to the influence of the chemotherapy drugs. In the early stage, it could be reduced in white blood cells. In severe cases, the number of blood cells, red blood cells, and hemoglobinin would decrease to varying degrees, leading to complications such as infection, organ bleeding, and may also lead to leukemia. 4. ** Toxic effect of the urine system **: - Some chemotherapy drugs (such as platinum-based chemotherapy drugs in the process of metabolism through the kidney, fluorouracil-based chemotherapy drugs) have direct superficial damage to the kidney and the urological system, which may cause kidney damage, leading to glomerulonetis, kidney incompetence, and even failure. 5. ** Toxic effect on the cardiovascular system **: - It was mainly manifested as a variety of cardiac arrest disturbances, myocartis, cardiac muscle damage, heart failure, etc. Among them, the most common ones were anthracyclines (such as epirubin, doxorubin, etc.). The targeted therapy of trastuzhu, fluoruron, taxol, high-dose cyclosporine, etc. may also cause it. 6. ** Other aspects **: - The general reactions included local phlebitis, tissue necrosis, chills, fever, swelling, fatigue, night sweats, etc. - There may also be lung toxicity, which is mainly manifested as paranoid pneumonias and lung edema. Some drugs (such as yew drugs) have neurotoxicity, which will cause numbness in the hands and feet, pain in the legs below the knee, etc., and their toxicity will accumulate. Anti-tumor drugs may also have sensitizing effects and allergic reactions, with a high incidence rate. Liver injury related to anti-tumor drugs mainly refers to liver injury caused by anti-tumor drug therapy or auxiliary drug therapy or reactivation of the original carrier of the liver virus. There may be situations such as liver cell necrosis and hepatic vein hemorrhage. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
What are the side effects of general targeted therapy drugs?
The side effects of targeted therapy mainly included the following aspects: 1. Digestive tract reactions: The targeted drug may stimulate the digestive tract, causing nausea, vomiting, diarrhea, abdominal distension, and other symptoms. This is a relatively common side effect. In addition, the combination of targeted drugs and chemotherapy may also cause a digestive reaction. 2. Liver and kidney toxicity: The drug may be digested in the liver or kidneys after blood circulation, which may increase the burden on the liver and kidney. When used in large doses, it may cause liver and kidney incompetence. 3. Fetal toxicity: Some special targeted drugs have fetal toxicity, such as trastuzumi, which easily passes through the placental barrier and may cause fetal abnormality. Pregnant women should avoid using such targeted drugs with strong fetal toxicity. 4. Others: Fever, chills, bone marrow suppression, allergy (very few patients are allergic to the targeted drug components), and other conditions may occur. In patients treated with Herceptin, symptoms and signs of decreased cardiac function may occur. During the period of taking the medicine, there may be adverse reactions such as peeling, pain, inflammation, etc. In addition, a sudden increase in dosage would cause fluctuations in blood concentration, affect the efficacy, accelerate drug resistance, and even cause serious adverse reactions. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
What are the best chemotherapy drugs for head and neck cancer?
For patients with relapsed or metastasized head and neck cancer, the commonly used first-line chemotherapy drugs included platinum, 5 -flurfluralin, taxane, cetuxed, and methylethalin, but it was not easy to determine which drug was the "best". There are different recommended combinations for different situations and different tolerance levels: - The standard first-line treatment was platinum-based chemotherapy in combination with 5 -flurfluralin, taxane, or cetuxed. - For patients who could not tolerate 5 -fluralin, platinum/taxane in combination with cetuxed could be used; for patients who could not tolerate platinum, taxane in combination with cetuxed could be used; for patients who could not tolerate the combination therapy, platinum, taxane, methylethrin, cetuxed and other single agents could be used. - In second-line treatment, patients who had not used taxoids before could use taxoids in combination with cetuxed; patients who had not used cetuxed before could use cetuxed alone; others could use chemotherapy alone that had not been used in first-line treatment. In addition, in the rhythmic chemotherapy protocol, methylethalin could be used as a commonly used oral chemotherapy drug for head and neck cancer. In short, the choice of chemotherapy drugs needed to take into account the patient's general condition, tumor location, tumor stage, pathological type, and other factors, weighing the pros and cons of the treatment method. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
What are the side effects of cancer drugs on the liver?
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What are the effects of taking targeted drugs in the late stage of liver cancer?
There may be the following symptoms when taking targeted drugs for late-stage liver cancer: - If the condition was under control and the tumor growth was suppressed, the tumor might shrink. - For patients with late-stage liver cancer who developed ascitic fluid, if their stomachs gradually subsided after taking the targeted drug, it might mean that the ascitic fluid decreased and the condition was controlled to a certain extent. - The patient's condition was stable. For example, although the tumor did not shrink after taking the targeted drug, its growth rate slowed down. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
What are the side effects of breast cancer chemotherapy drugs?
The side effects of breast cancer chemotherapy drugs were as follows: 1. Bone marrow suppression: - White blood cell reduction was more common. For example, white blood cell reduction was more common after the use of cyclosporine, and the lowest value was 1 - 2 weeks after the use of cyclosporine. Most of them recovered after 2 - 3 weeks. The strength of bone marrow suppression caused by anthracyclines was higher than that of cyclosporine. Bone marrow suppression was more likely to occur when taxane drugs were used in combination with cyclosporine. Bone marrow suppression could lead to low white blood cells, low blood counts, and even leukemia. Neutropiuria could also be accompanied by infection. 2. ** Intestinal reaction **: - This included loss of appetite, nausea, vomiting, diarrhea, or constipation. Cyclocyclosporine's digestive tract reactions were manifested as loss of appetite, nausea and vomiting, which generally disappeared after stopping the drug for 1 - 3 days. Anthracyclines would cause digestive disorder, such as nausea, vomiting and diarrhea. The digestive tract reactions of taxane drugs were common but not serious, and a few could have diarrhea. 3. ** Cardiac toxicity (mainly due to anthracyclines)**: - The greater the dosage, the greater the cardiac toxicity. There were three types according to the time of appearance: - Acuteness: It often occurs within a few hours or days after administration, and is manifested as cardiac transmission disorder and cardiac arrest. In a few cases, it is manifested as pericarditis and acute left heart failure. - "Chronical: It occurs within 1 year of chemotherapy, and it is manifested as left cardiovascular malfunction, which can eventually lead to heart failure." - Late-onset: It occurs several years after chemotherapy, and may manifest as heart failure, myocardiopathic disease, and cardiac arrest. 4. ** Hair Loss **: - 60 - 90% of patients who took the anthracyclines would have hair loss, which was generally irreversible. After stopping the drug, hair would grow back; mild hair loss was more common with taxane drugs; taxol, a commonly used drug for breast cancer, could also cause hair loss. 5. ** Others **: - Cytoxan has urological reactions. If a large dose of cyclosporine is used and there is no effective preventive measures, it can cause bleeding cystitis, which is manifested as bladder irritation symptoms, oliguria, hematuria, and proteinuria. The occurrence rate is relatively low when the conventional dose is used. There may also be stomatitis, toxic leukemia, skin hyperchrominosis, menstrual disorder, and lung edema. Poisonous Poisonous (appearing on the side of the tongue and sub-tongue on the fifth to tenth day of medication). There were reports of occasional fever, chills, hives, hyperchromism, and joint pain; Allergy to yew drugs (Paclitaxel-like and taxotere can cause it, but not taxol. Pretreatment with hormones and other drugs is required before infusion. The drip rate can be adjusted for mild symptoms. For serious reactions, the drug should be stopped.), peripheral nervous system toxicity (Numbness of fingers and toes is the most common. Obvious sensory and motor disturbances and decreased tendon reflexes may occur at high doses. Grand mal seizure during infusion is reported in some cases.), cardiovascular toxicity (Temporary heart rate and low blood pressure are more common), joint and muscle pain (about half of the patients will feel pain 2 - 3 days after taking the medicine, which is related to the dosage and will recover within a few days. When combined with the White Increasing Needle, the muscle pain will worsen), changes in the liver and gallbladder system (such as elevation of Bilirubin, Alkaline Phosphatase, and Glutamate Oxalic Transaminases in some patients after taking taxol). In addition, chemotherapy drugs could also cause local reactions, such as phlebitis caused by chemotherapy drugs, local skin rupture and necrosis caused by drug exudate, as well as immune suppression, which would cause the body's immune function to be low and the resistance to infection. There were also internal organ damage, such as liver and kidney function damage. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
What are the side effects of breast cancer chemotherapy drugs?
At present, there was no clear mention of which breast cancer chemotherapy drugs had fewer side effects. The common side effects of breast cancer chemotherapy drugs included digestive tract reactions, bone marrow suppression, hair loss, rash, impact on cardiac function, local inflammation, radiation inflammation, radiation inflammation, and so on. The side effects of different drugs were different, but there was no mention of which drug had fewer side effects. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
What are the side effects of oral hormonal drugs for breast cancer?
The following side effects may occur in breast cancer patients who take oral hormonal drugs: 1. Menopacus-like symptoms, such as hot flashes, night sweats, dry vaginas, itching, etc., may also appear anxiety, insomnia and other psychological symptoms, which is a direct manifestation of the decrease in the level of estrogens in the body caused by drugs. 2. Hot flashes, joint pain, bone loss, cardiovascular disease, etc. may occur. 3. For patients who took tamoxifen, there was a possibility of the development of Endometrial Cancer, so they needed to undergo regular gynecology examinations. 4. Taking an Aromatase Inhibition may cause bone thinning. 5. Luteinizing Hormone-Releasing Hormone-Anomalies may cause adverse reactions such as hot flashes, decreased libido, and mood changes. They may also have adverse reactions to bone thinning and the cardiovascular system. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
There are several types of breast cancer targeted drugs
There were mainly the following types of breast cancer targeted drugs: 1. Anti-neoplastic targeted drugs: There are intravenous preparations and oral drugs, but the effect in the treatment of breast cancer is not ideal. For example, bevacidol (Avastin) will be considered in some cases. 2. Anti-Her- 2 targeted drugs: targeted at HER - 2 positive patients, it is the most important targeted drug for breast cancer, mainly including trastuzumab (Herceptin), pertubizab, dm- 1, lapatini, etc. The prerequisite for use was that the patient was positive for HER - 2 (+++ in the immune tissue test). If the immune tissue test was ++, the patient would need to undergo a further FISH test. The patient could only be used if the FISH test was positive. If the immune tissue test was + or-, the patient could not be used. 3. A targeted drug for patients with fetal mutations in the Brca lineage: The main drug is olaparib, which is used to treat patients with metastasizing breast cancer who have harmful or suspected harmful mutations in the Brca lineage and who are negative for the human embryonic growth factor receptor 2 (HEL2). 4. Immune therapy (in a sense, it was also a targeted drug): Anti-PD- 1/PD-L1 Monoclone Antibodies, which essentially relieved immune suppression and activated immune cells to kill cancer cells. 5. mTO inhibition drugs, such as everolimus and sirolimus, can inhibit the activation of the mTO signaling pathway, thereby suppressing the growth and metabolism of tumor cells. 6. Other targeted therapy drugs, such as Parp inhibition drugs, CD 4/6 inhibition drugs, etc. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
Is it always effective to take targeted drugs for lung cancer?
The effect of targeted drugs on lung cancer patients was not very good. Target drugs could not cure lung cancer. Although they could prolong survival time, they could not always be effective. There were very few driver mutations in lung cancer, so there were relatively few targeted drugs that could be used. When using targeted drugs, it was necessary to find the target of lung cancer and could not be used blindly. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>