Such a cartoon is probably very odd and inappropriate. It might stem from someone's warped imagination or an attempt to shock for no valid reason. There's really no legitimate or good purpose behind it.
The main traits of Archie type comics include vibrant characters, likeable personalities, and situations that are easy to relate to. They often deal with common teenage issues and emotions in an entertaining way. The art is often clean and appealing, making them visually engaging for readers of all ages.
When a cartoon kid turns into a monster, it often sets the stage for a wild and unpredictable journey. The kid might struggle to fit in with the normal world or use the newfound powers for good or evil. It could also trigger a series of events that reveal hidden secrets or uncover a larger conspiracy.
A good comic strip with a villain is interesting when the villain poses a real threat and challenges the heroes in unique ways. Also, if their design and powers are visually appealing and creative, that adds to the appeal.