In fanfiction, Sasuke might save Sakura from Orochimaru by using his Sharingan. His powerful eyes could detect Orochimaru's moves and counter them, allowing him to rescue Sakura.
In many Sasuke - Sakura - Gaara fanfictions, Sasuke saving Sakura from Gaara can be a really exciting plot. It often shows Sasuke's strength and his hidden feelings for Sakura. Maybe he uses his Sharingan to outwit Gaara's sand attacks and rescue Sakura just in time.
Sasuke could save Sakura from Orochimaru by outsmarting him. Since Sasuke is very intelligent, he might come up with a clever plan to get Sakura away from Orochimaru's clutches.
In this kind of fanfiction, Itachi might use his powerful Sharingan abilities. He could perhaps create illusions to mislead Orochimaru and his minions, then quickly snatch Sasuke away. For example, he could make Orochimaru think that Sasuke is in a completely different location while he secretly approaches and rescues him.
One possible scenario could be Naruto arriving just in time as Orochimaru is about to perform a dangerous jutsu on Sasuke. Naruto uses his new Rasengan variant, overpowering Orochimaru and rescuing Sasuke. It would be a very action - packed moment.
In the fanfiction, Itachi might be acting according to some secret mission that endangers Sakura's life. Sasuke, who has a strong bond with Sakura now, won't let that happen. He jumps in and uses his ninja skills. Sasuke could have developed some new jutsu that he uses to counter Itachi's attacks. This not only saves Sakura but also shows Sasuke's growth as a ninja. And Sakura, in turn, might be in the middle of researching some important medical ninja stuff that Itachi's actions could have disrupted if not for Sasuke.
Naruto's character might develop a stronger sense of purpose. Saving Sasuke becomes more than just about their friendship; it could be about righting a wrong in the ninja world. His resolve to save Sasuke would make him train harder and become more strategic in his battles.
One possible plot twist could be that Sasuke has been under a genjutsu that makes him target Sakura, and Naruto has to break the genjutsu first to truly save her. Maybe the one who cast the genjutsu is a new, powerful enemy who wants to disrupt the bond between Team 7. Naruto, with his strong will and newfound powers, manages to find the source of the genjutsu and free Sasuke from its control, thus saving Sakura from harm.
Sasuke's character could develop in terms of his loyalty. By saving Sakura from Itachi, he shows his loyalty to his friends and comrades. He is no longer just the revenge - driven Sasuke. He has grown to care about others' safety.
One common theme is the display of Sasuke's heroism. He is often depicted as the strong and capable ninja who can overcome Gaara's power to save Sakura.