In the fanfiction, Itachi might be acting according to some secret mission that endangers Sakura's life. Sasuke, who has a strong bond with Sakura now, won't let that happen. He jumps in and uses his ninja skills. Sasuke could have developed some new jutsu that he uses to counter Itachi's attacks. This not only saves Sakura but also shows Sasuke's growth as a ninja. And Sakura, in turn, might be in the middle of researching some important medical ninja stuff that Itachi's actions could have disrupted if not for Sasuke.
Sasuke's character could develop in terms of his loyalty. By saving Sakura from Itachi, he shows his loyalty to his friends and comrades. He is no longer just the revenge - driven Sasuke. He has grown to care about others' safety.
In this kind of fanfiction, Itachi might use his powerful Sharingan abilities. He could perhaps create illusions to mislead Orochimaru and his minions, then quickly snatch Sasuke away. For example, he could make Orochimaru think that Sasuke is in a completely different location while he secretly approaches and rescues him.
In many Sasuke - Sakura - Gaara fanfictions, Sasuke saving Sakura from Gaara can be a really exciting plot. It often shows Sasuke's strength and his hidden feelings for Sakura. Maybe he uses his Sharingan to outwit Gaara's sand attacks and rescue Sakura just in time.
In this kind of fanfiction, perhaps Itachi uses his quick reflexes and ninja skills to catch Sakura as she's about to fall. Maybe she was in a dangerous situation like on a crumbling cliff or a collapsing building. Itachi, being the powerful ninja he is, swoops in just in time to prevent her from getting hurt.
The main characters are obviously Itachi and Sakura. Itachi, the complex and powerful Uchiha from the Naruto series, and Sakura, the intelligent and strong - willed kunoichi.
One common theme is redemption. Itachi is often seen as a tragic figure in need of saving, and Sakura becomes the instrument of his redemption. Another theme is the power of friendship or love. Sakura's actions are usually driven by her feelings for Itachi, whether it's a deep friendship or something more romantic.
In fanfiction, Sasuke might save Sakura from Orochimaru by using his Sharingan. His powerful eyes could detect Orochimaru's moves and counter them, allowing him to rescue Sakura.
Well, in such a fanfiction, perhaps Sakura is in a very dark place mentally, feeling hopeless and considering suicide. Itachi, with his perceptive nature, might notice her distress. He could use his skills and wisdom to talk her out of it, maybe by sharing his own experiences of dealing with difficult situations in the ninja world. He would offer her hope and a new perspective on life, making her realize that there are always reasons to keep living.
One popular 'sakura saves itachi' fanfiction is 'A Different Path'. In this story, Sakura uses her medical skills and newfound ninja abilities to change Itachi's fate. It shows an interesting take on their relationship and how Sakura's determination can rewrite the events that were supposed to happen.