Not really. While there are all kinds of themes in Naruto fanfiction, this isn't one that pops up all the time. Most fanfictions tend to focus on things like Naruto's relationships, his growth as a ninja, or his adventures. Experimentation on Naruto isn't as widespread a theme, but it does exist in some more creative and out - of - the - box fanfictions.
Well, 'naruto experimented on fanfiction' might suggest that within the realm of fan - created stories about Naruto, there are plots where Naruto is the subject of some kind of experimentation. This could be physical experimentation, perhaps related to his ninja abilities, or it could be more of a social or psychological experiment where his character is put in unusual circumstances to see how he'd react. For example, a fanfiction might have Naruto being experimented on by an enemy to try and extract the secret of his chakra power, or he could be part of an experiment within his own village to improve his combat skills in a new and untested way.
Naruto could develop a new sense of determination. He might be determined to not let Orochimaru's experiments define him. Instead, he could use what has happened as a motivation to become stronger in his own way. He may also start to study more about the type of experiments Orochimaru was doing, not to replicate them, but to find ways to counter any future threats related to that kind of science.
Perhaps the experiments by Cadmus would change Naruto in unexpected ways. His powers could be altered, and he might develop new abilities or lose some of his old ones. This could lead to a conflict within Naruto as he tries to come to terms with these changes. His friends in Konoha might initially be suspicious of him due to his altered state. But Naruto would strive to prove that he's still the same person at heart and use his newfound or remaining powers to protect his village from any threats related to Cadmus.
He survives through his strong will. Naruto has an unwavering determination that refuses to be broken by Orochimaru's experiments. His inner strength and the chakra of the Nine - Tails within him might also play a role in withstanding the physical and mental torture of the experiments.
Perhaps Naruto starts to have a connection to Orochimaru's other experiments or creations. He might find himself in a situation where he has to either help or fight these other 'products' of Orochimaru's mad science. Also, the fanfiction could explore how Naruto's friends react to what has happened to him. Do they trust him still? Or are they afraid of what Orochimaru might have turned him into?
Obviously, a female version of Naruto would be the main character. She would be at the center of the story, dealing with the consequences of the experimentation.
One common theme could be exploring the unique challenges a female Naruto might face in a world dominated by male shinobi. For example, she might have to deal with different expectations regarding her strength and abilities.
At first, Naruto would probably be excited. He's always eager to get stronger, so he might see this as an opportunity. He'd trust Tsunade because she's the Hokage and a respected medical ninja. But if the experiments got too painful or started to seem strange, he'd start to question things. He might try to talk to Tsunade about it, but in his Naruto - like way, still be respectful.
One possibility is that Tsunade is trying to find a way to enhance Naruto's already formidable chakra control. Maybe she's experimenting with new medical - ninjutsu techniques to see if she can make Naruto's body even more resilient in battle. This could lead to Naruto having to endure some painful procedures but ultimately emerging with new powers.