One possible plotline could be that Naruto accidentally travels back in time and lands right in front of Tsunade when she was at a crucial point in her life, like just after the death of her loved ones. Naruto, with his future knowledge, helps her cope and in the process, they grow closer. Another plotline could be that Tsunade is sent to the future where she meets an older and more mature Naruto. They initially clash due to their different outlooks from different times but then gradually fall in love as they understand each other better.
In a time - travel scenario, Naruto could go back in time and meet a younger Tsunade. His knowledge of her future self might make him initially approach her with a sense of familiarity. Tsunade, on the other hand, would be intrigued by this strange boy. Their relationship could start as a friendship, with Naruto gradually showing Tsunade a different perspective on life and ninja values. As time passes, they might start to develop deeper feelings for each other, based on mutual understanding and shared experiences in this altered timeline.
Often, Orochimaru can be a main antagonist. Since he has his own devious plans in the Naruto universe, in a time - travel scenario, he might oppose Naruto and Tsunade's attempts to change things for the better. He could be trying to use the time - travel chaos to his own advantage, like stealing forbidden jutsu from different eras.
Often, Orochimaru can still be a main antagonist. Even in a time - travel scenario, his thirst for power and immortality doesn't change. He might oppose Naruto and Tsunade's attempts to change the past as it could disrupt his own plans for power.
A Naruto and Tsunade time travel fanfiction can be really interesting. It could involve them going back in time to change certain events in the Naruto universe. Maybe they go back to prevent a great tragedy or to save a beloved character. For example, they might travel back to the time of the Uchiha massacre and try to stop it, which would completely change the course of the story.
In some 'naruto x tsunade time travel fanfiction', an interesting plot could be that Naruto and Tsunade travel back to a time when the Hidden Leaf Village was just being founded. They have to deal with the primitive and often dangerous situations of that era. Naruto might introduce some future - like ideas to help build the village, while Tsunade uses her medical skills and leadership to gain the trust of the early villagers. It's also possible that they face challenges from other ninja clans who are not so welcoming of their new - fangled ways.
Another plot could be that Tsunade uses her medical knowledge along with Naruto's power to go back in time and heal some of the major wounds the ninja world has suffered. They could go back to the time of the First Hokage and help him build a more peaceful and prosperous ninja world from the start. In this way, they might avoid all the wars and conflicts that followed.
In a time - travel scenario, Naruto's exuberant personality could initially shock Tsunade. But as they spend more time together, Naruto's determination to protect might make Tsunade see him in a new light. His growth and understanding of the past could also intrigue her. Maybe they'd start off as comrades trying to fix things in the past, and slowly feelings would develop as they rely on each other more and more.
Perhaps they travel back to a time when Tsunade was younger and more reckless. Naruto, with his experience, tries to help her avoid some of the mistakes she made in her past. This could lead to a different relationship between them, as Naruto becomes a sort of mentor to the younger Tsunade. And along the way, they might start to develop deeper feelings for each other that were not present in the original timeline.
In some fanfictions, the plot might involve Naruto and Tsunade time - traveling to an era where they are forced to hide their identities. This secrecy and the need to rely on each other in a strange time could lead to a romantic connection. Another interesting plot could be that they travel back to a time when Tsunade was being courted by other men. Naruto, with his unique charm, manages to win her over. Or there could be a plot where they time - travel and end up in a parallel universe where the rules of their relationship are completely different, and they have to navigate this new world while their feelings for each other grow.