I don't have enough information to say for sure. It could be fiction, or it could have roots in reality that have been adapted or exaggerated for a particular purpose.
Definitely not. 'Runner Runner' is purely a work of fiction. The plot and characters are made up to engage the audience and offer an exciting viewing experience.
The story of Anger Sierra might focus on Sierra's battles with her own anger, how it shapes her personality and the challenges she faces because of it. It could also involve her growth and transformation in dealing with this emotion.
I don't believe it's true. Most of the time, when a story has a name like that, it's made up to capture our interest and take us on a fictional journey rather than being rooted in reality.