I'm not sure specifically about 'big titted grandma stories' as it's not a common mainstream topic. But in general, stories can be interesting if they are about unique characters. However, this kind of description might be considered inappropriate or disrespectful in many contexts.
Well, 'One Piece' has a few characters with big proportions. But remember, it's more about the adventure and story than just the character designs. The diverse characters contribute to the rich world-building of the series.
Most movies focus on stories that can resonate with a broad range of viewers. Stories that involve objectifying or inappropriate concepts like this are not likely to be made into movies. There are, however, movies that explore transgender issues in a more positive and educational light.
I'm not aware of any mainstream 'turned into big titted tranny stories' in traditional literature. Most literature focuses on more positive and inclusive themes that don't involve such objectifying or inappropriate concepts.
Well, we can focus on the grandma's character traits like her love and care. For example, we could tell a story about a grandma who has a big heart (not literally in the inappropriate sense) and always welcomes everyone with open arms. Forget about the inappropriate physical description and emphasize her positive actions like knitting warm sweaters for the family.
Educate yourself on proper language use. Know what is considered inappropriate in different contexts. Replace offensive words with neutral or positive ones. For instance, if it's about a character, describe their good qualities instead of using disrespectful terms.
Fat loss was a method that used modern technology to reduce stubborn fat in the human body through specific instruments and techniques. There were two main principles for fat loss: one was to use a fat bursting device to emit high-energy sound waves or ultrasound waves. By vibrating and rubbing the fat cells, it caused them to self-explode, thereby breaking down fatty acid and expelling it out of the body. The other method was to use focused ultrasound or strong sound waves to impact and destroy fat cells, dissolving them into free fatty acid and expelling them through metabolism. These methods could be applied to different parts of the body. They were safe, effective, and difficult to rebound. However, the specific operation method, frequency, and effect still needed to be determined according to different fat loss devices. In general, fat loss was a healthy way to lose weight, but the specific effects and scope of application needed further understanding.
As a Fat Man was a the mainland of China that told the story of Eva, a supermodel. She had the face of an angel and the body of a devil, but she had a special physique. She could only eat a few dozen grains of rice a day, or she would become fat. However, when she met Ruan Dongsheng, the former school idol, she realized that she would not get fat as long as she ate his cooking. Eva began to rely on Ruan Dongsheng for food and her figure, and gradually developed feelings for him. This drama was a sweet and immature love story.