His relationship with Kakashi would be severely affected. Kakashi has always taught Naruto about right and wrong, and Orochimaru is clearly on the wrong side in Kakashi's eyes. Naruto becoming a fan would make Kakashi feel like he has failed as a teacher. Also, with Sakura, she would be very concerned. She might think Naruto has been influenced by some dark power, and this could cause her to distance herself from Naruto, at least until she understands what's really going on.
It would likely strain his relationship with Sasuke. Sasuke has his own complex history with Orochimaru, and if Naruto becomes a fan, Sasuke would be very confused and probably angry. He might see Naruto as betraying their shared values. As for his friends in Konoha, they would also be worried and try to talk Naruto out of it, which could lead to some arguments and a rift in their friendships.
Well, his friends would likely be very confused and hurt. They know Naruto as a determined and kind - hearted person. If he's brainwashed, they might initially try to reach out to him, thinking it's just a temporary state. But as time goes on, they could become distrustful if he starts to act against them. Sasuke, for example, might be even more conflicted, seeing Naruto in such a different state. And Sakura would be heartbroken, as Naruto has always been a source of hope and friendship for her.
When Naruto becomes Hinata, his relationship with Naruto's friends would be complex. He'd be in a female body and have to navigate through the different expectations society has for Hinata. His relationship with Kiba and Shino, Hinata's former teammates, would become more personal as he now shares Hinata's memories and feelings. And his relationship with Naruto's old crush, Sakura, would be a bit awkward as he tries to act like Hinata.
With his friends in Konoha, they would be worried and perhaps a bit afraid. They know Orochimaru's reputation as a villain. Naruto's friends like Shikamaru might start to keep a closer eye on him, which Naruto could resent. He would feel like they don't trust him anymore, and this could strain their friendships.
His friends might respect him more for having a useful new skill.
Well, it would be a huge blow to his friendships. Naruto's friends are drawn to his big heart and strong emotions. An emotionless Naruto would not respond in the same warm way. He might not share in their joys or sorrows. Sakura, for instance, would miss his determination and the way he used to encourage her. His friends would have to work hard to reach out to him, but they may also start to drift apart because the emotional connection is no longer there.
His relationship with Sasuke would become really complex. Sasuke, as an Uchiha, might feel a mix of jealousy and concern. Jealousy because Naruto now has a part of what makes the Uchiha special, and concern because he knows the dangers of the Sharingan. They might have more intense battles or training sessions as Sasuke tries to understand how Naruto got the Sharingan and how it's affecting him.
If Naruto got a new bloodline in the fanfiction, it could strengthen his relationship with Sasuke. Sasuke, always interested in power, might be intrigued by Naruto's new abilities and see him in a new light. They could start training together again to understand and master the bloodline, which would bring them closer as friends and rivals.
It could strengthen his relationship with his friends. For example, they might be in awe of his new power and support him in mastering it. His friends could also help him find new ways to use the glass - controlling ability in battles.
For his friends in Team 7, Sakura would be initially shocked but then try to find medical ways to help Naruto if the tail causes any discomfort or problems. Naruto's new state might also attract the attention of Hinata, who would be even more shy around him but also very supportive. And with the villagers, those who once feared or hated him might start to see him in a new light as this unique development could be seen as a sign of his growing power and importance.
His relationship with Sasuke would be really interesting. Since Sasuke has his own complex connection to the Uchiha clan and Madara, Naruto becoming a Madara fan could either bring them closer together in understanding the Uchiha's past or drive them further apart if Sasuke doesn't agree with Naruto's new - found admiration. Maybe Naruto would start to push Sasuke towards a more 'Madara - like' view of power and revenge.