Hope love interest is Jean grey or Emma frost or Susan storm or hela or sif
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LIKEI hope for Susan... Even if Reed truly loves her it doesn't change the fact that he is a sh*tty husband... (for crying out loud she cheated on him to feel loved and from what I have heard she once showed up before him stark naked and even then he still chose tinkering with the 'toys' in his lab)
The best way to make Sue a love interest in my opinion, is to just make Reed the Maker (the version of Reed from the Ultimate comics). That Reed is evil and a full-blown villain. No qualms with NTRing a villain.