Aside from Old Vulture, who had a speed that could accelerate through the time area, the eyeless big beast, and the demon lady's powers were affected. Their powers were unable to land on Han Sen.
The time area was unable to stall them for very long. Their powers still tried to strike them in the end.
"Bao'er, take it!" Han Sen threw the Nine-Spin Destiny Mirror to Bao'er. He took out his cause karma knife. He threw it in the air and used his mouth to bite the cause karma knife.
At the same time, Han Sen pulled out another weapon. It was Fox's Charming God Jian.
The cause karma knife was powerful, but its primary power was the cause karma. It dealt little much damage by itself. In a fight this intense, it would have been difficult for it to be of much use. Han Sen would have had to wait until he was injured before making use of it. Only then would it have benefitted him.