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Colorado on his last breath ended injecting himself with a deadly drug made out of the blood of the cloned aliens, infesting his body not only with a drug that enhances his psychic power, but also with the cancerous blood cells of these "failed" clones.
Because it was impossible to replicate the DNA of this alien race, these clones were all malformed failures whose entire bodies were covered on mutated body parts and cancerous tumors. Blood from such beings was obviously going to be a terrible ingredient for the drug.
Yet as a last resort, the doctor ended using it, aiming to enhance his psychic powers and regenerate, but ending up getting both with the price of becoming an abomination that couldn't stop screaming in agony.
His body bloated and resembled a massive, aberrant baby covered on bleeding cancerous tumors. And his huge forehead ended developing the small gray-skinned head of a child of this alien race.