Isolation. The misunderstood MC often feels alone because others don't get them. For instance, in many stories, the MC might have a special power or come from a different background that others can't fathom, so they are left on their own most of the time.
One example could be 'Re:Zero − Starting Life in Another World'. At first, Subaru is often misunderstood by the characters around him. His strange behavior and repeated resets of the timeline make it difficult for others to fully comprehend his motives and actions.
Sure. There's a Gay MC Story about an MC who uses his art to fight against homophobia in the hip - hop world. He raps about the importance of equality and respect, and his story is one of perseverance. He faces a lot of backlash from some traditionalists in the genre but still stands his ground.
This novel is a modern romance novel about a wealthy family. It tells the story of the female protagonist who was schemed against by a traitor and left the male protagonist six years ago. Six years later, she returned with her child, but the male protagonist's misunderstanding of her deepened. The female protagonist wanted to use her own strength to save the male protagonist and return the framing to him. This novel fits the plot of the female lead you're looking for.
Some official fan communities dedicated to the source material of 707 and the MC might also have fanfic sections. These communities are a great place to find fan - created content, as the members are usually very passionate about the characters and share their own works or recommend others' works.
In 'Echoes of Separation', the MC's personal growth and changing priorities cause them to leave the ML. The character development is quite intense in this one.
You might want to check out 'Dragonborn'. The MC is a dragon who undergoes a journey of self-discovery and battles against powerful foes. The world-building and character development are really engaging.