Are painkillers effective?The effectiveness of painkillers was not absolute.
First of all, in terms of gender differences, some painkillers might be slightly less effective for women. Because most of the pain relief drugs were tested on male mice, and most of the test patients were male, the effectiveness of the drugs was mostly targeted at men, and there was actually a slight difference in the efficacy of the drugs between men and women. Moreover, women had a higher chance of suffering from neuropathic pain such as arthrosis, neuromyoma, and headache. At the same time, women were twice as likely to be diagnosed with anxiety as men. Mental states such as anxiety could amplify a person's pain. These factors combined to make painkillers less effective for women.
Secondly, from the types of painkillers and the symptoms they were used for, different painkillers had their own scope of application. For example, Ibuprofen was often used to relieve mild to moderate pain such as headache and joint pain, but its pain-relieving effect was relatively weak; Ketofen patches were mainly used for pain caused by tendon sheath inflammation, rheumatism, scapularis periapsis, trauma (no wound or skin damage), etc.; Celecoxib had little irritation to the digestive tract and strong painkiller effect, which was the first choice for most orthopedic doctors to treat disc protrusion pain. If the painkillers used did not match the symptoms, the effect might not be good.
Moreover, from the use of painkillers, painkillers could not be used for a long time. Regular use might cause tolerance, resulting in no effect after taking them.
In addition, although the human body will release intrinsic opioids when in pain, their strength and durability are not strong enough. Opioids that act on the receptor will cause addiction and a series of adverse side effects, and their effects are not completely ideal.
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Can you share some real stories about painkillers?Sure. There was a story of a person who had chronic back pain. After trying various therapies, they finally found a painkiller that worked well for them. It significantly reduced their pain level and allowed them to resume normal daily activities like walking and sitting comfortably. However, they had to be careful with the dosage to avoid potential side effects.
What are the arthritic painkillers?The following are some capsule drugs for pain relief in arthritic patients:
1. Nabumetone capsules: It is a non-acidic anti-inflammatory drug and is widely used in the treatment of rheumatism. The painkiller effect can last for 24 hours and has less adverse effects on the digestive tract.
2. "Huoxue Zhitong capsule: It is composed of Angelica, Pseudoginseng, and Ground beetle. It has the effect of reducing swelling and relieving pain, promoting blood circulation and dispersing blood stasis. It can be used to treat arthralgia syndrome caused by blood stasis (knee arthrosis belongs to the arthralgia syndrome category of traditional Chinese medicine). However, it is prohibited for children under six years old, pregnant women, and people with abnormal liver and kidney function. This product cannot achieve the treatment effect for arthralgia syndrome belonging to other syndrome types. It should be used according to the doctor's advice.
3. Compound Sailong capsule: It can dispel cold and dampness, dredge collaterals and relieve pain. It has a certain effect on general pain, including joint pain.
4. Ibuprofen Sustained Release Tablets: It is more common in daily life and can be used to relieve pain in arthritic patients.
5. Celecoxib capsules: It can be used to relieve pain in arthritic patients.
6. [Diclofenac Sustained Release Tablets: It can be used to relieve pain in arthritic patients.]
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What kind of painkillers are there?Painkillers can be divided into the following categories:
1. Non-steroid anti-inflammatory drugs, such as Aspirin, Ibuprofen, Naproen, Fenbufen, Ketofen, Oxaprazine, Celecoxib, and Amrecoxib, were the most common in clinical practice. Their painkiller effects were relatively weak, and they were not addictive. They were widely used, and their efficacy was relatively accurate. They could be used for common pains such as colds, fevers, muscle soreness, colds, fatigue headaches, and neuropathic pain. Some of them were irritating to the digestive tract.
2. Central painkillers: The typical example was tramadol sustained release tablets, as well as bucinarizine, rotondine, and flurfluralin. They were mainly used to relieve postoperative pain.
3. Anaesthetic painkillers: Common ones include morphine, Demerol, and oxcodone (Oxy Contin, Tylenin). They are all representative anesthetic painkillers of opioids. They are very effective in relieving pain, but long-term use is easy to become addicted. They are mainly used to treat cancer pain.
4. Antispasmodic painkillers: mainly used to treat smooth muscle spasmodic pain, such as atropine, scopolane, etc., can be used to relieve spasm of the digestive tract.
5. Anti-anxiety painkillers: represented by Valium, which can be used to relieve headaches, especially neuropathic headaches.
6. Painkillers for neuropathic pain: Carbamazuron, gabapentin, and pregabalin.
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Are painkillers good for women?Painkillers were good for women, but it depended on the situation.
For women with menstrual cramps, if it was primary menstrual cramps (there was no organic disease in the abdomen, it was usually caused by the increase in the content of prostaglandins in the uterus), Western medicine painkillers such as Ibuprofen Sustained Release capsules and diclofenac Sustained Release Tablets could relieve the symptoms of menstrual cramps by suppressing the synthesis of prostaglandins. Traditional Chinese medicines such as Yuanhu Painkiller and Aifu Nuangong Pill could also be used to relieve primary menstrual cramps. However, if it is secondary menstrual cramps (there are organic diseases in the abdomen, such as anorexia, adenomyosis, Pelvic inflammation, etc.), it is not recommended to use painkillers alone. The primary disease needs to be actively treated.
In other areas of pain, such as joint and muscle pain, headaches, etc., women can also use painkillers to relieve pain. However, painkillers also have some potential risks. For example, some painkillers may cause irritation or burden to the digestive tract, such as gastric acid aversion, pain, loss of appetite, indigestion and other symptoms after taking them. Long-term use may also induce diseases such as gastroenteritis and gastric ulcers; Some drugs have kidney toxicity or liver toxicity. Long-term use may have negative effects on the health of the kidney and liver. Therefore, they should be used with caution and taken in a fixed amount according to the doctor's advice to avoid blindly taking the medicine by themselves.
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Is there any dependence on painkillers?Some painkiller injections had problems with dependence. For example, some painkillers would become reliant after long-term use. The duration of the effect would gradually decrease, and the interval between injections would become shorter. For example, painkillers such as morphine would develop tolerance after continuous use for 3 - 5 days, and it could lead to dependence after more than 1 week. However, it was only used for acute severe pain with a clear cause of pain and would not be addictive after short-term use (such as one injection), or for severe pain in advanced cancer. In addition, in painkillers, the problem of addiction was often directed at injections, because injections would cause the blood concentration of the drug to rise rapidly, which might produce euphoria. However, the situation was different for people who were in real pain.
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What are the ancient painkillers?Ancient painkillers included willow bark and asari. Willow bark contained a substance called Salicolic acid, which had antipyretic and pain-relieving effects. Salicolic acid was extracted from willow bark in the 19th century, and after acetification, it became the modern name of the commonly known Aspirin. Asari is often used for various cold pains, including headache, joint pain, toothache, heartache, stomachache, etc. It can also be used for general pain caused by cold meridians. It can also be used externally as an anesthetic for various pains such as trauma and rheumatism. Modern pharmacology studies have also shown that Asari has antipyretic, sedative, anti-inflammatory, and pain-relieving effects. It also has a certain local anesthetic effect. The anesthetic effect of 50% Asari decoction is close to 1% procaine.
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