bioisostere replacement success stories

Having traveled to America in the year 1862, this was the beginning of a dream, the finest of times. What constitutes a true master of success? Having some notable descendants hardly counts for anything. To build an Oil Empire alongside Rockefeller To place Carnegie on the throne of the steel magnate To help Ford propel the industrialization of automobiles worldwide To lead Edison to monopolize the future of the electrical industry To be an Angel Investor for Morgan's capital Hear this, applause!

Marchioness Harriet Goldlane, a talented noblewoman, made a deal with Old Duke Almandine. To save her younger brother, she was willing to become a substitute for Liam's 'mate', the grandson of the Old Duke. Liam was an Alpha whose 'mate' died long ago. He was severely injured and had been living without a heart for a long time. He could only wake up from his sleep when there was a full moon. The Old Duke and Liam himself guessed that the man would die soon due to his worsening condition. Because of that, Old Duke wanted Harriet to give birth to an heir to the Almandine Family from Liam's seed so that their family would have a new leader. The Alpha's replacement bride would soon find that she was in love with the dying man and now they both wished for a miracle to save Liam's life. Could she fulfill her duty to bear the next Alpha for the Almandines? Would Liam survive to protect his bride and family?

A few minutes before her wedding, Jeslyn found out her soon-to-be husband was only after the benefit he would get by marrying her.  Heartbroken and feeling betrayed, she opted for the only option available at that moment, which was to get into a contract marriage with whichever man she could find, or else her family's fortune would end up in the hands of her enemies.  … "Mister, please, will you marry me?" She asked him. A man she saw entering the restroom of the wedding venue. 'He must be one of the guests,' she thought. Maverick was taken aback by that proposal. He saw her flinch when he turned to look at her. It was apparent she got scared of him, yet she composed herself, ready to dive into the mystery before her. "It will be a marriage contract. We will get a divorce after one year," he heard her say. He also needed a woman for his brat, so he responded, "Deal." Unbeknownst to her, she just made a deal with the sweetest devil that could ever exist.  ... He is the nightmare of country M, a country where evil rules. She is the little bunny raised with love and affection. Hurt a fly? No, she had never done that before. However, forced to become the demon's wife, she had no choice but to shed her fake persona. What little bunny? Who said she could not step on a pianist's fingers with her heels and pretend like she didn't mean it? Ha, those celebrities want to play the pity card? Do they want to garner the sympathy of the public? Well, why again is she called a 'little bunny'? Isn't it because she was the best at acting cute? Did no one tell these white lotuses wanting to dive into her husband's bed that she stole his soul when she spanked his naughty son? .... Drop by my discord to have a one on one discussion with your author-- Hassy_101. Link below https://discord.gg/CswFCgc2

A smug smile appeared on her step sister's lips when she finally revealed she was actually pregnant with her mate's child. Her father's futile attempt to apologize, for ignoring her all this time, because he had his own reasons and asked her to understand. A plea of forgiveness from her mate as he begged her not to reject him, claiming it was just a stupid mistake that he shouldn't have made. And to top it off, a cursed alpha from the north, to whom her step sister was actually promised, is here to collect his debt, so she has to take her place as the sacrifice now. Darn!

Emily is considered a curse by her father, who abandoned her to live alone in the countryside the day she was born. However, when Emily comes of age, her father asks her to marry another man in place of her sister. She fights back but is poisoned by her father and stepmother, leaving her mute and without her wolf. Her fiancé, Alpha Klaus, is said to be nothing more than a head wolf with an empty title, and he's short-tempered and cruel, but is that really the case? "Tell me, why did you run away from your marriage?" Alpha Klaus puffed on his cigarette, sunglasses hiding his face, "Did you not want to marry me because you were afraid of me?" She fled, he chased. Wherever she was, he found her. She was treated like grass by her family, he treated her like a treasure. He sheltered her from the wind and rain and healed her from all her wounds. He took her in his arms, a warm snort in her face, and he whispered in her ear, "Emily, I ask you to think of me every day, just as I miss you." I want the rest of your memories to be with me. " Note: This book deals with adult content, violence and dark magic.

Amara, a wealthy aristocrat's well-bred daughter with a secret to hide, is thrown into despair when her world is suddenly shattered after discovering she isn’t the Caldwells' biological daughter. It was incredibly convenient for her father to discard years of love, devotion, and family ties, quickly sending her as a marriage tribute to a Werewolf Prince after receiving an invitation that, according to the Peace Treaty between Werewolves and Humans, required one of his daughters. It no longer mattered that she wasn’t truly a Caldwell, nor that she was already in love with someone else. So, on the night of her planned elopement with her lover, her fate with the monster was ruthlessly sealed. Forget that the Alpha Prince is a cursed monster—yet, why is he always in her face, treating her like his perfect plaything to pass the time? But most importantly, if he truly doesn't care about her, why do those who cross her suddenly disappear or get punished? — Excerpt: Amara could feel the tension in the way Alexander stood before her—the restraint in his silence, the weight of his attention pressing against her body. He shouldn’t be this close to her after cornering her against a tree. “Do you know what happens when I want something?” he asked, his voice dangerously controlled. Her breath trembled, but she shook her head. “I—I don’t know.” “I take it.” Amara inhaled sharply as she lifted her gaze to meet his dark, conflicted eyes, burning with something that made her heart stutter. “Then why haven’t you?” she whispered. His gaze dropped briefly to her lips. “Because if I cross that line,” he said, “I won’t stop.” “Then cross it.” Her voice was barely audible. Instantly, the restraint in Alexander’s eyes shattered. He lowered his head and claimed her mouth in a desperate, hungry kiss.

Sebastian Leodegrance was fated to bring about the world's end, his path irrevocably marked by the three scars etched across his left eye as proof of his unholy contract with Ardalas, the Evil God. His insatiable thirst for power would have been enough to conquer all, even without the infernal blessing, but now not even the divine intervention of the Goddess could thwart his ambitions. With purposeful strides, he marched toward Cassiopeia to claim the hand of the renowned Princess Ava Cassia, a woman whose veins coursed with the blood of greatness. But as he drew closer, he discovered that the Princess had been exchanged with her Lady in Waiting. "Yes. I am the replacement. You have been fooled!" *** "From now on, Isla, call me Elder Sister." The person in front of her was the brightest constellation in the world. Ava Cassia... the Princess who was even prettier than the Nereids. But it was like looking in the mirror. She looked exactly like her. "Maybe the Goddess sent you to me so we can become Sisters. How about it, my dear Isla? Would you call me Sister?" Her most cherished treasure; her Elder Sister, Ava. "I'm sorry, Sister... this is the only way." "You must replace me. Because if I bear his child... this world would perish..."

She love but got betrayed... She love but got cheated... Her heart is whole yet heartbroken... She promise that she will gave her grandfather a life full of happiness. She promise that she will make those who left them regret! It was not revenge that urge her to live. It was happiness! Revenge? Nah. I'll kill them with success! Will Min Ju still say the same if her enemies make their move? You knew that isn't the case. Her choices will change for good or for worst... Whatever her choices may be. Qing Wu Yao will stay by her side and her family will support her behind her back. Achieving success wasn't an easy task. There are some outside force that was trying to bring her down. The jealousy of a woman. The anger of a powerful man who hold a card that might bring Min Ju to ruin. Things that was lost will came back. And things that was already there will be lost. Many things happenened that change her strategy. She planned not to raise her hand but she was force to by her enemies. At last, Min Ju never thought that she'll pull the trigger to end everything. [Disclaimer: The cover is not mine. Credits to the wonderful owner] - - - Sneek Peek: "Are you in love with me?" "What if I say yes? Would you let me enter your life?" "Prove me that you're worthy." #2 "What do you think about my granddaughter?" "She was very talented. But what I like the most about her is her smile. Everytime I look at her, I fall in love at every sight."

A book I took from the net; all credit belongs to Leil lowndes

A car accident robbed Nadira of her memory, leaving her to mistakenly believe that Aditya was her true love. She married into wealth, only to find herself trapped in a living nightmare. Her sister Aisha's schemes, her husband's icy cruelty, the dehumanizing abuse in prison, the wrongful conviction, and the terminal diagnosis all drove her to despair. "Countdown," Adi started counting down, "Five, four..." Bang. Nadi bent her knees. Her knees hit the cold, hard cement surface with a loud sound. The rainwater in the puddles splashed high. "Aisha, I was wrong." "Louder!" Adi ordered Nadi, even pressing her neck to make her kowtow. Nadi's heart ached desperately as the man who had loved her for many years forced her to kowtow to Aisha, the real culprit behind all this self-directed drama. She was wrong. She shouldn't have fallen in love with Adi! If she hadn't loved Adi, would all this not have happened? In the end, she took her own life, bringing a tragic close to her suffering existence. Reborn with the memories of her past life, Nadira vowed to change her destiny. She performed on the streets, hoping to reunite with Reza, the man she had truly loved in her previous existence. Their love transcended time and space, blossoming anew, from the sweetness of their school days to the solemn exchange of wedding vows. Reza enveloped her in unwavering devotion, building a fortress of happiness around her. Meanwhile, Aditya, also reborn, could only watch from the shadows, consumed by regret and longing.