Naruto's Sage Mode would be really useful. He could use it to sense the zombies from a greater distance, and its enhanced physical abilities would make it easier for him to take on zombies. Also, he might develop new jutsus based on the situation. For example, he could create a jutsu that immobilizes zombies in a large area. His ability to communicate with nature in Sage Mode could also help him find safe places or sources of food and water that are hidden from the zombies.
One common plot twist could be that Naruto discovers some of his friends have been secretly bitten and are turning into zombies. For example, Sasuke might get bitten but try to hide it from Naruto at first. Another could be that the zombie virus is actually created by an old enemy of the Hidden Leaf Village who has found a new way to attack. Maybe Orochimaru had something to do with it and his experiments went wrong, leading to the apocalypse.
One idea could be Naruto using his shadow clones to distract the zombies while he and his team find a safe place. Maybe he discovers a new jutsu that can control the zombies instead of just defeating them.
The plot could start with Naruto waking up to the zombie apocalypse already in full swing. He quickly realizes his powers are enhanced in this situation. He then sets out on a journey to find other strong shinobi who might also be alive. As he travels, he has to deal with different types of zombies, some with special abilities. Eventually, he uncovers a conspiracy that links the zombie apocalypse to an ancient evil that was sealed away long ago, and he has to face it to save the world.
It could be amazing. A godlike Naruto in a zombie apocalypse would likely use his super - powerful jutsu to fend off the zombies easily. For example, his Rasengan could be used to blast away hordes of zombies at once. Maybe he could also use his shadow clone jutsu to create multiple copies of himself to search for survivors or guard a safe zone.
His speed would be even more important. He could quickly move around zombies and avoid being bitten. For example, using his Rasengan, he could blast through groups of zombies easily.
Sonic's speed allows him to be a great scout. He can cover large areas in no time to find safe places or look for resources. His ability to spin dash can also be used as an offensive move against zombies. Tails, on the other hand, could use his two tails to fly and get a better view of the surroundings. He could also use his knowledge of mechanics to jury - rig weapons from the debris around. For instance, he might make a makeshift flamethrower using some old parts and a fuel source, which would be very effective against zombies.
A possible plot could be that an unknown enemy uses a powerful jutsu that accidentally creates zombies. The story could start with Naruto and his friends in Konoha noticing strange behavior among some villagers. As the situation worsens, they realize it's a zombie outbreak. They then have to band together, find out the source of the outbreak, and try to stop it while also protecting the remaining survivors.
The ninja in the Naruto world are used to combat and danger. In a zombie apocalypse, characters like Kakashi could use his intelligence and wide range of jutsu. He might use his Earth - Style: Earth Wall to create barriers against the zombies. As for Hinata, her Byakugan could be used to see zombies from afar, giving the group early warning. And the teamwork among them, which is a staple in the Naruto series, would be their greatest strength in this new and terrifying situation.
Survival is a very common theme. The characters, Naruto and the OC, have to find ways to stay alive in a world full of zombies. They need to get food, water and shelter.