Another plot could involve a love - related betrayal. Suppose Sakura is in love with someone who is an enemy of her village in secret. To protect this person, she betrays her village's secrets. It could create a lot of drama as her friends discover her actions.
It often changes drastically. Sakura may initially feel hurt and angry. She might start to question all her previous beliefs about Naruto. For example, if Naruto betrays her trust in a battle situation by seemingly siding with the enemy, Sakura's view of him as a reliable friend and teammate would be shattered.
One possibility could be that in a ninja world setting, Sakura and Hinata are forced to betray their friends due to a powerful enemy's blackmail. Maybe the enemy has kidnapped their families and threatened to harm them if they don't cooperate. This could lead to a rift in their relationships with Naruto and the others.
Perhaps in the fanfiction, Konoha betrays Sakura by spreading false rumors about her. They could say she's been collaborating with the enemy, which would damage her reputation not only in the village but also among her friends. This would lead to her being ostracized and feeling deeply betrayed by the place she once called home.
Naruto could also feel a deep sense of hurt. After all, he has been through a lot with Sakura. In the face of her betrayal, he might start to question his own judgment of people. However, being Naruto, he would not give up easily. He might try to find a way to redeem Sakura or at least make her see the error of her ways. He would draw on his own experiences of being ostracized in the past and use that to try to understand her actions and find a solution.
One possible plot could be that they are betrayed by a supposed ally in their ninja village. Maybe this ally was envious of their skills or popularity. For example, the ally could spread false rumors about them, which would lead to them being shunned by some of their comrades. This would create a lot of emotional turmoil for the girls as they try to clear their names and figure out why they were betrayed.
One possible scenario could be Naruto being forced into a situation where he has to seem to betray Sakura to protect her from a greater danger. For example, he might be blackmailed by an enemy into staying away from her or acting against her interests.
In some fanfiction concepts, Sasuke might betray Naruto due to his unwavering pursuit of power and a different view of the ninja world. Sakura could be involved perhaps out of misguided loyalty to Sasuke. It could start with Sasuke believing Naruto is a hindrance to his goals and Sakura following Sasuke's lead, breaking Naruto's trust.
The consequences would be far - reaching. Naruto, being the optimistic and friendly character he is, would be deeply hurt. His power might be affected as his emotional state is in turmoil. He could also start to view the ninja world in a different light, seeing it as a place where even the closest friends can turn on you. This could lead to him making different choices in his battles and relationships, and may even push him towards a darker path himself in some fanfiction interpretations.
Hinata could lose her usual shy and gentle demeanor. The act of betrayal might force her to be more assertive, but in a negative way. She might become more defensive and less empathetic towards her former friends.