Another reaction could be that she tries to find a way to redeem Konoha. Despite the betrayal, Sakura might still have some love for the village. She could work towards changing the situation from within, trying to fix what has been broken and make Konoha a place she can be proud to call home again.
Well, Sakura could also try to understand why her friends betrayed her. She might be the kind of character who looks for the root cause of the problem. She could approach her friends, not to forgive them right away, but to have a conversation. By doing this, she hopes to find out if there was some misunderstanding or if they were forced into betraying her.
He could be initially shocked and heartbroken. Naruto has always been loyal to Konoha, so such a betrayal would hit him hard. He might go into a state of disbelief for a while.
Sakura could become very angry. She has been let down by those she trusted, and anger is a natural response. She might lash out at her friends or distance herself from them immediately. For example, she could say some harsh words to them in the heat of the moment.
Naruto could also feel a deep sense of hurt. After all, he has been through a lot with Sakura. In the face of her betrayal, he might start to question his own judgment of people. However, being Naruto, he would not give up easily. He might try to find a way to redeem Sakura or at least make her see the error of her ways. He would draw on his own experiences of being ostracized in the past and use that to try to understand her actions and find a solution.
At first, Naruto is often shocked. He can't believe that the village he has always loved and fought for would turn against him. Then, he might feel a deep sense of sadness. In some fanfictions, he tries to reason with those who betrayed him, asking them why they did it.
He might initially try to prove his innocence. He'll gather evidence or find people who can vouch for him. But as the situation worsens, he could become angry and more determined to find out the truth and expose those who are behind his false accusation. He might even leave Konoha to seek answers and allies elsewhere.
Naruto would probably be very angry at first. He has always considered Konoha his home and to be betrayed by it would be a huge blow. He might initially try to reason with the villagers, thinking it's a misunderstanding. Hinata, on the other hand, would be more likely to be heartbroken. She's more reserved and the thought of her village turning against her would be deeply painful.
Naruto would likely be extremely hurt. He has always considered the Konoha 11 as his friends and comrades. So, at first, he would probably be in denial, trying to figure out what went wrong. He might try to talk to them, to understand their reasons.
In some fanfics, Naruto initially tries to reason with the people of Konoha. He believes that there has been a misunderstanding and he wants to clear his name. But when he realizes that no one is listening, he becomes angry and frustrated. He might start to lash out at those who are hunting him.
Sasuke might initially be shocked. He has always seen Sakura as someone connected to Konoha, so her leaving would be unexpected. He could be concerned about her safety, especially if she leaves without proper preparation or protection.