It could be a very compelling read. If the fanfic manages to capture the complex personalities of Victoria Neuman and Hughie, it has the potential to be great. Victoria's mysterious and powerful nature combined with Hughie's more relatable and underdog-like qualities can create interesting storylines. For example, they could be on opposite sides initially, with Victoria's hidden agenda clashing with Hughie's pursuit of justice in the world of 'The Boys'.
Character development. If the fanfic shows how Victoria and Hughie grow and change because of their interactions, it will stand out. For example, Victoria might start to question her own motives when she spends time with Hughie, who has a more straightforward sense of right and wrong.
Once upon a time, Hughie and Victoria found themselves in a rather strange situation. They were both on a mission to expose a corrupt supe. Hughie was his usual nervous self, but Victoria was determined. They sneaked into a Vought building, hiding in the shadows. Hughie accidentally knocked over a small object, making a noise. Victoria quickly signaled for him to be quiet. They continued on their way, finally finding the evidence they needed. It was a long and dangerous journey, but their friendship grew stronger through it all.
One common theme is the power dynamic. Given the nature of 'The Boys' universe, exploring how Victoria's power and Hughie's more 'ordinary' (in comparison) self interact is popular. For example, how he copes with her abilities.