I'm not sure what your question is, but from what I know,"give up and I'll hold on" is not a common term or theme in online novels. If you can provide more context or information, I will try my best to answer your question.
Give up on me and hold on tight. I'm adapted from a novel.
There are many stories in the novel, some of which may involve the theme of giving up and holding on. One of the most famous novels is probably the Harry Potter series, in which Harry Potter experienced many difficulties and challenges in his pursuit of the Sorcerer's Stone, but in the end he succeeded in seizing the opportunity and obtaining the Sorcerer's Stone.
Other famous novels include Dream of the Red Chamber, Water Margins, Romance of the Three Kingdoms, etc. They all contain stories about the theme of giving up and grasping on.
For a comic to have a tight fit, it might involve precise panel layouts, efficient use of dialogue, and a focused storyline that doesn't wander. Everything contributes directly to the main theme or conflict.