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What are the characteristics and applications of nanocrystals?

What are the characteristics and applications of nanocrystals?

2026-07-29 16:52
1 answer

Nanocrystal drugs had the following characteristics: 1. ** High safety **: Nanocrystal does not use a carrier to deliver, does not contain a large amount of surface active agents and carrier materials, and will not produce the material's metabolism products. 2. ** High Bioutilization **: By reducing the drug particles to the nano-level through the micro-powder treatment, the specific surface area of the poorly water-resistant drug is increased, and the dissolution and dissolution rate are improved. In addition, the drug has a greater surface stickiness, prolonging the effect time of the drug in the mucus layer, limiting the spread, increasing the local concentration of the drug, and promoting the absorption of the drug in the digestive tract. It can also make the effluxation transporter on the biological membrane saturated to improve the bio-utilization. 3. ** Increase drug potency **: It is suitable for Class II and IV drugs in the Biological Drug Class System (BCS), especially for Class II drugs. It greatly improves the drug potency of poorly water-resistant drugs. 4. ** High drug load **: In addition to the necessary stabilizing agent, there is no need for other auxiliary materials in the product. The drug itself is used as the delivery system, and the drug load capacity is high. 5. ** Simple prescription and process **: Only a small amount of surface active agents or high molecular materials are needed to obtain drug crystals with high drug loading and good stability, which is easy to produce on a large scale. Nanomedicines were widely used in the treatment of various major malignant diseases because of their targeting, high efficiency, and low toxicity. However, no more detailed information was found on the specific scope of application. Read more exciting novels for free

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