The main reasons for the formation of gastroesophagus reflex disease were as follows: 1. ** Abnormal structure and function of the esophagus anti-reflex barrier ** - ** Lower esophagus constrictor (LES) related factors **: - Temporary relaxation of the lower esophagus constrictor (TLEPR), which is a temporary relaxation in the LES area without swallowing, is an important cause of the reflex. - Some diseases, such as hiatal hemorrhoids and achalasis of the esophagus, can lead to the functional disorder of the lower esophagus, causing the structure and function of the LES to be abnormal. - Some foods (such as coffee, chocolate, strong tea, etc.) not only stimulate the increase of gastric acid secretion, but also lead to lower esophagus constrictor malfunction; there are also drugs such as nifeprid (a drug to treat high blood pressure), Diazepam (a sedative), etc., which can also cause lower esophagus constrictor malfunction. - ** The anti-reflex effect of the diaphragm foot is weakened **: The structure of the gastric-esophagus junction (including the diaphragm foot at the gastric-esophagus junction, the diaphragm esophagus tendon, the His angle between the esophagus and the stomach, etc.) is an important guarantee for the anti-reflex function. If the structure of the diaphragm angle is damaged by some factors, it will lead to the weakening of the anti-reflex barrier. 2. ** Weak clearance of esophagus **: This is related to the abnormality of esophagus itself. When the clearance of esophagus on the waste is weakened, the residual waste will damage the esophagus and lead to a vicious cycle. 3. ** Lower esophagus membrane barrier function ** - ** Pre-ocular factors **: Problems in the mucus layer and the concentration of HCO3-on the surface of the mucus membrane. - ** Epidermal factors **: Abnormality of the connecting structure between the cells, the transport of the cells, the buffer system in the cells, and the metabolism of the cells. - ** Post-epitheial factors **: The basic acidic state of the tissues and the blood supply are not good. When the mucus membrane defense barrier is damaged, even normal reflex can lead to Reflux Empyropathy (RE). 4. ** Stomach factors ** - High-fat diet, excessive eating, and obstruction of the gastric outlet will lead to a decrease in the speed of gastric emptying, which will easily cause the gastric contents to flow back into the esophagus. - When gastric acid is secreted too much, it is easier to cause gastric acid to flow back into the esophagus. 5. ** Peritoneal cavity factor ** - Obese, pregnancy, strenuous exercise, tight clothing, etc., the abdominal pressure increases, making the stomach contents easy to reverse flow into the esophagus. In addition, patients with constipation and patients with large amounts of ascitic fluid (such as hepatic ascitic fluid) could also have increased abdominal pressure, which could lead to changes in the pressure or function of the lower esophagus constrictor, which could lead to gastric-esophagus reflex disease. 6. ** Other possible factors ** - Although there was no clear conclusion on the relationship between helicobactor pylon (HP) and gastroesophagus reflex disease, some studies found that HP infection in the stomach could significantly increase the maximum acid secretion (MAO) and basic acid secretion (BAO). The gastric acid content that flowed back into the esophagus would cause damage to the esophagus. - From the perspective of traditional Chinese medicine, the basic mechanism was that the liver and gallbladder were not smooth, the spleen was not healthy, the stomach was not harmonious, and the stomach qi went up and invaded the esophagus, causing a series of clinical symptoms. Read more exciting novels for free
Stomach distension may occur in the stomach due to gastric emptying delay and gastric and Duodenal dyskinesia. If a patient with gastroesophagus reflex has symptoms of abdominal distension, it is recommended to seek medical attention in time, identify the cause, and treat it under the guidance of a doctor. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
The treatment of gastroesophagus reflex disease was a long-term process. For patients with uncomplicated gastroesophagus reflex disease, treatment measures include lifestyle adjustments, such as raising the head of the bed by about 15cm; avoiding the use of strong stimulants that cause gastric acid secretion (such as coffee and alcohol); avoiding certain drugs (such as anti-cholic drugs), food (fat, chocolate), and smoking; One hour after meals and before going to bed, 30ml of antacid was given to neutralize gastric acid and may increase the tension of the lower esophagus constrictor; Use H2 blocking agent to reduce gastric acid (sometimes combined with other drugs); use of a cholic stimulant (For example, uracholine 25 milligrams, three times a day; metoclopramine 10 milligrams, oral 30 minutes before meals and before going to bed; cisapride 10 milligrams, four times a day); H+ -K+ jumped adenases such as Omepraz (20 milligrams/day, continuous 4 - 8 weeks) or Lansoprazole (30 milligrams/day, continuous 4 - 8 weeks) to promote the rapid healing of digestive esophagus. Omepraz can also be used to prevent the relapse of corrosive esophagus. In terms of drug therapy, the first line of drugs was the proton-pump-inhibition drugs (such as prazoles). Their main function was to suppress gastric acid secretion, but there would be side effects caused by insufficient gastric acid secretion. Therefore, they should be taken in combination with protective agents for the gastric mucus (such as aluminum magnesite, Na-Alginate, etc.) and gastric prokinetic drugs (such as mosapride, itopride, cicilliride, etc.). The histamin H2 receptor antagonist (such as ranitidine, famotine, etc.) was not as effective as the proton-pump antagonist. For patients with mild symptoms (once or twice a week), it might be used. If the symptoms could not be completely relieved, then consider taking the proton-pump antagonist. During the medication period, it was also necessary to use a combination of a gastric kinetic drug and a mucus membrane protective agent according to the doctor's advice. If the symptoms could not be improved, antacid drugs such as Na-hydrogen-carbonate-could be added. If the symptoms still existed after two weeks, low-dose proton-pump-inhibition drugs such as rabeprazole-Omeprazole-could be added. For complications (such as bleeding caused by esophagus, esophagus stricture, Barrett's metaplasias, etc.). In addition to massive bleeding, bleeding caused by esophagus does not require emergency surgery but can recur. Patients with esophagus stricture should be treated with active medical treatment and repeated expansion, such as omeprazol, lansoprazol, or anti-reflex surgery.(For example, Belsey, Hill, Nissen) is often used for patients with severe esophagus, bleeding, stricture, ulcers, or difficult to treat symptoms. Regardless of whether there is a hiatal hemorrhoid, the surgery can also be performed with laparoscopy assisted by television. The effect of medical or surgical treatment on Barrett's metaplasias is inconsistent. It is often recommended to perform an examination with laparoscopy (once every 1 - 2 years) to monitor the possibility of malignant transformation of this metaplasias. In addition, according to the symptoms, the symptoms of esophagus were divided into liver and stomach heat stagnation, liver qi invading the stomach, liver depression and spleen deficiency, liver depression and blood stasis, etc. There were corresponding treatments and prescriptions, but it was easy to relapse, often due to improper diet and emotional discomfort. In addition to drug treatment, daily life also needed to pay attention to health care, such as avoiding excessive eating and drinking. In summary, regardless of the comprehensive use of multiple treatment methods, the possible relapse of the disease, the treatment of complications, and the adjustment of lifestyle, long-term treatment should be adhered to. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
In addition to avoiding the use of calcium antagonist in patients with gastroesophagus reflex disease, Other types of antihyperbaric drugs can be used, including diuretics, beta-receptor blockades, Ang I, Ang II, and Ang II receptor antagonist (ARB, such as irbesartan). However, it should be noted that the specialist should decide which drug to take according to the patient's condition. At the same time, it should be paid attention to whether it interacted with the treatment drugs for esophagus (such as antacid, gastric prokinetic drugs, etc.). <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
The severity of the disease was quite serious. This was a disease caused by the irritation or damage of the throat by the gastric and Duodenal acid. In terms of symptoms, the patient would have sore throat, foreign body sensation in the throat, or blockage, and other discomfort symptoms. It might also be accompanied by irritation in the esophagus such as acid aversion, heartburn, chest pain, etc. In severe cases, it could cause swallowing pain. A small number of patients did not have obvious acid and heartburn, but they had a feeling of swallowing and choking, as well as cough, wheezing, sore throat, oral ulcers, sinusies and other extra-esophagus irritation. Judging from the nature of the disease, it was a chronic disease that required long-term life and diet management. If it was not controlled, the continuous stimulation of the return fluid might cause the inflammation of the throat to occur repeatedly, affecting the patient's quality of life. Moreover, the sour symptoms after the occurrence of gastroesophagus reflex sore disease may be more severe, making the patient feel particularly uncomfortable. In terms of treatment, it required a combination of many methods. On the one hand, it was treated with medication. The main medication needed to be used continuously for four to eight weeks before gradually stopping the medication. On the other hand, surgery could be evaluated for patients who did not have a good effect on medication or could not tolerate the side effects of long-term medication. In addition, the patient also needed to manage his life and diet, such as eating a light diet, avoiding spicy food, eating less, and exercising after eating to reduce the time the food stayed in the stomach. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
The following methods can be used to deal with gastro-oesophagus reflex: ** 1. Medication ** 1. ** Prokinetic drugs, antacid drugs, and antacid suppressors ** - According to the severity of the symptoms, choose to use it alone or in combination. Combined medication can relieve patients with severe symptoms quickly. 2. **H2 receptor antagonist ** - For example, cimetidine, ranitidine, and the like. 3. ** Proton pump inhibition ** - For example, Omeprazo, Pantoprazol, and so on. 4. ** Protective agent for gastric mucus membrane ** - For example, bismuth-pectate, sucralfate, and the like. 5. ** Anti-anxiety medication (for patients with related conditions)** - For example, paroxi, alprazolam, and the like. 6. ** Traditional Chinese Medicine ** - If sour acid is difficult to swallow, the tongue is thin and white, and the stool is not smooth, you can refer to Qi stagnation and stomach pain granules, which can improve liver qi stagnation, chest distension and abdominal cavity pain. - If there was burning discomfort behind the sternum and the stomach cavity, dry mouth, bitter taste, red tongue and yellow moss, Zuojin Pill could be used to improve it. It was effective for symptoms such as bitter taste, noisy mouth, vomiting and sour water caused by liver-fire invading the stomach. - He could also use traditional Chinese medicine to strengthen the stomach, suppress acid, and soothe the liver to harmonize the stomach. He could refer to Chaihu Shugan San. ** 2. Surgery ** 1. ** Lateroscopic fundoplication ** - He could reconstruct the esophagus and stomach angle without opening the chest and abdomen. He could also reduce the length of the esophagus hiatus and reconstruct the valve of the stomach and stomach. If the drug treatment is not effective, it can be considered. 2. ** Anti-Reflux Surgery Under the Enscope ** - For example, radio frequency therapy was a commonly used method of treatment under the microscope, which had good efficacy and high safety. Anti-gastric reflex surgery was performed by removing part of the cardiac mucus and using the scar contracture during the healing process to shrink the cardiac mucus to achieve the purpose of anti-gastric reflex. However, this method was relatively rare. ** 3. Lifestyle improvement ** 1. ** In terms of diet ** - You can't eat too much. It's recommended to eat less and eat more. Reduce the amount of food you eat at each meal and eat more vegetables, fruits, and coarse grains. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
Certain antihyperbaric drugs should be used with caution in patients with gastroesophagus reflex, such as alpha receptor blockade agents (such as terazobin) and calcium channel blockade agents (such as nifedipine). This was because these drugs might relax the lower esophagus constrictor, causing the symptoms of gastroesophagus to worsen. However, the specific medication adjustment must be carried out under the professional guidance of the doctor. You can't just stop the medicine or change the medicine yourself. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
Intestinal metaplasias caused by gastric esophagus may be more serious. Long-term gastric esophagus could lead to many diseases, such as esophagus, inflammation, inflammation, and so on. The stimulation of chronic inflammation could cause intestinal metaplasia. In severe cases, intestinal metaplasia could lead to cancer. However, don't panic too much. Pay attention to your daily habits, actively treat and control your development. For example, find out the cause, and perform surgical intervention when necessary (for example, when there are anatomical changes such as cardiac relaxation, esophagus hiatus, and poor medication effects). At the same time, combine medication and diet conditioning to help the recovery of digestive function. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
Octopus was not suitable for patients with gastroesophagus reflex. Octopuses were highly irritating. Eating too much of them might increase the burden on the esophagus and aggravate inflammation. Octopuses might also be greasy. In addition, they took a long time to digest, which could easily induce a reverse flow phenomenon. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
The main reason for the discomfort in the throat when there was gastric acid in the stomach was that the gastric acid and other stomach contents irritated the throat. Under normal circumstances, the lower esophagus was like a valve that could prevent the contents of the stomach from flowing back to the esophagus and throat. However, if the valve was loosened or there was a problem, the gastric acid and bile in the stomach would flow up and pass through the esophagus to the throat. Stomach acid was very corrosive, and the mucus membrane of the throat was relatively delicate. After being stimulated by stomach acid, there would be discomfort, such as a foreign body sensation in the throat, a burning sensation, and sometimes pain, coughing, and so on. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>
Wenweishu Granules were suitable for the treatment of superficial asthma and chronic atrophic asthma. They had the effect of promoting qi, relieving pain, warming the middle and nourishing the stomach. Generally, they had little significance in the treatment of reflex esophagus. However, if there were symptoms such as abdominal distension and belching in the stomach, they could also be treated with Wenweishu Granules under the guidance of a doctor. It should be noted that patients with gastroesophagus reflex should not take Wenweishu granules without authorization to prevent the medicine from delaying the disease. <a href="/?from=ask_words" style="color:red" target="_blank">Read more exciting novels for free</a>