In terms of her relationships with other Slytherins, the boys in the house might either be overly protective or try to take advantage of her. Some of the Slytherin girls might see her as a threat, especially if she's getting more attention from the boys or from the teachers. But there could also be a group of Slytherin girls who form a strong clique with her. And her relationship with Dumbledore could be one where he tries to encourage her to break free from the more traditional and sometimes dark Slytherin values, seeing her as a potential force for good in the house.
If Tsuna were a girl, her relationship with her male friends might become more complex. For example, some of them might develop romantic feelings for her. Her friendships with female characters could also change. They might become more competitive or more sisterly depending on the nature of the story.
If Naruto were a girl, her relationship with Sasuke would likely be more complex. There could be an underlying romantic tension from the start. Sasuke might be more protective of her. And with Sakura, instead of a love triangle, they could become best friends who support each other in their ninja careers. Also, Kakashi might train her a bit differently, perhaps being more lenient at times because of her gender.
In a family setting, her relationship with her parents might also shift. Her father might become more protective, while her mother might start to have more mother - daughter type of conversations with her. And with siblings, there could be new dynamics depending on whether they are older or younger. If she has an older brother, he might be more protective too, and if she has a younger sister, they could become closer as sisters often do.
With Hermione, he might see her in a new light. Instead of looking down on her as a Mudblood, he could admire her intelligence. They could work together on a project to improve the education system in the wizarding world. He would learn from her, and they could develop a mutual respect that was absent in their original world.
When Shirou turns into a girl, her relationships with other characters are bound to be different. Her male friends might start to see her in a more delicate way, even if she still has her old - Shirou - like strength. There could be a change in the power dynamics within the group she belongs to. Her relationships with female characters could range from being mentored by them in how to be a girl to facing competition from them. And any romantic relationships she had or hoped for would need to be re - examined, as the gender roles and expectations are now different.
If Arthas turns into a girl, her relationships with male friends might become more complex. For example, some might see her in a new, romantic light. Her friendships with female characters could also change. They might be more empathetic towards her situation or be jealous of her new - found attention.
Her relationship with Naruto would be different. Instead of the typical male - male rivalry, there could be a more complex dynamic. Naruto might be more protective of her at times, or there could be a romantic undertone to their friendship. With Sakura, they could become closer as two strong female characters. Sakura might see Sasuke as an inspiration for her own growth. And with Kakashi, he would have to adjust his mentoring style as Sasuke is now a girl, perhaps being more cautious and aware of the different challenges she might face.
In terms of his relationships with his Slytherin peers, some might look down on him. But others could be intrigued. Pansy Parkinson, for example, might see Draco as a girl as a threat to her status as the 'queen bee' in Slytherin. However, some of the more open - minded Slytherins could befriend Draco and help her deal with the challenges of being a girl in a very traditional and often misogynistic wizarding society.
Well, considering Harry, his relationship with the other Gryffindors could be affected. Some might think he has turned to the 'dark side' since he is now under Snape's care. But others might understand that Harry has no choice in the matter. Draco's relationship with Hagrid could be very interesting. Hagrid might be very cautious around Draco now that he is with Snape. And Snape's relationship with the other Hogwarts professors would also change. Some might be more understanding, while others might think Snape is overstepping his boundaries. But overall, these new family dynamics would cause a ripple effect throughout the wizarding world.
In terms of her enemies, they might try to use her gender against her. They could spread rumors or try to undermine her in battles by taunting her about her secret. However, this could also backfire as it might make her more determined to prove herself as a strong fighter regardless of her gender.