Maybe there's a plot where they all get trapped in a genjutsu that makes them relive their worst memories, but they help each other break free. They realize just how much they mean to one another as they support and comfort each other during this difficult time. This could strengthen their bond even more and lead to new adventures with a stronger friendship at the core.
A really interesting plot could be that a powerful enemy targets their friendship specifically. The enemy tries to create misunderstandings between them. But Naruto, Sasuke and Sakura are smart enough to see through the lies. They then work together to defeat the enemy and prove that their friendship is unbreakable. This would involve a lot of emotional moments as well as action-packed scenes.
A really interesting plot could be that Sakura and Sasuke are transported to an alternate universe where they are the only ones from their world. They have to figure out how to get back while also dealing with the strange new world. During this time, they rely solely on their friendship. They might meet different versions of their friends and enemies, and their bond is put to the test as they make difficult decisions about whether to stay or go back to their own universe.
In a fanfiction, there could be a story where a mysterious enemy targets Sasuke, Naruto and Sakura specifically because of their unique bond. The three of them then have to go into hiding and figure out who the enemy is and what they want. Along the way, they rely on each other's strengths and grow even closer as friends.
How about a story where an unknown enemy creates clones of them? Naruto, Sasuke, and Sakura have to not only fight these clones but also figure out who the enemy is and why they are being targeted. Along the way, they might discover new powers within themselves and also learn more about their relationships with each other.
Maybe a plot where Sasuke and Sakura go on a mission together, and Naruto's family has to step in to help when things go wrong. For example, Sasuke and Sakura are sent to investigate a strange occurrence on the outskirts of the village. But they get trapped, and Naruto's son, using his unique skills learned from his father, manages to find and rescue them, strengthening the ties between the families even more.
One plot idea could be Sai trying to understand the deep bond between Naruto, Sakura and Sasuke. He might initially struggle as he has his own unique upbringing. For example, he could be assigned a mission with the three of them and slowly learn about their history, like Naruto's determination to bring Sasuke back and Sakura's unrequited love for Sasuke in the beginning. This could lead to Sai having a new perspective on friendship and loyalty.
A possible plot could be that they discover a new and dangerous jutsu that has been lost for centuries. They decide to train together to master it so that it can be used for the good of the village. Along the way, they learn more about each other's pasts and their friendship deepens.
Perhaps a fanfiction where Sasuke loses his memory and Sakura has to help him regain it. She takes him back to all the places that are important to their past, like their old training grounds. As she tries to jog his memory, they end up reliving old memories and emotions, and this could lead to a rekindling of their relationship in a very emotional way.
Another plot could be a crossover with another anime world. Let's say they end up in the world of One Piece. They would have to learn about the new world, its rules, and make new alliances. It would be really fun to see how Sasuke's Sharingan, Naruto's Jutsu, and Sakura's medical skills would be useful in that completely different environment. And of course, no lemon content would be involved as it's just about their adventures in a new world.
One plot idea could be that the Sannin discover a prophecy that only Naruto, Sasuke, and Sakura can fulfill. So they take the three under their wings more intensively. Jiraiya focuses on Naruto's spiritual growth, Orochimaru on Sasuke's control over his dark powers, and Tsunade on Sakura's physical and mental strength. As they train, they also uncover secrets about the ninja world that could change everything.
One plot idea could be that in an alternate universe, Sasuke and Sakura have been in a relationship for a while. Naruto, being their close friend, witnesses their first real kiss during a moment of celebration after a big victory in the village. This kiss could symbolize the stability and love they've found in each other, and Naruto's reaction could be a mix of happiness for his friends and a tinge of his own loneliness.