One plot idea could be that the One Ring somehow finds its way into the X - Men universe. Maybe Magneto senses its power and wants to use it for his own purposes, believing it could give him ultimate control over mutants and humans alike. The X - Men, on the other hand, realize the danger of the Ring and try to stop Magneto from getting his hands on it. Another idea is that some of the LOTR characters are reincarnated as mutants. For example, Aragorn could be a mutant with enhanced leadership abilities and physical prowess, and he teams up with the X - Men to fight a common enemy that threatens both Middle - earth and the mutant world.
One idea could be that the One Ring somehow ends up in the world of Pirates of the Caribbean. Jack Sparrow, being the wily character he is, gets wind of its power and decides to either use it for his own gain or sell it to the highest bidder. The Fellowship, in turn, has to track it down in this strange new world full of pirates, sea monsters, and cursed treasures.
Another plot could involve the Rings of Power in LOTR having some sort of connection to the magic in Narnia. For example, the White Witch might be interested in obtaining the One Ring to increase her power. This could lead to a conflict where the forces of good from both Narnia and Middle - earth have to join together to stop her. The different races in both worlds, such as the hobbits, dwarves, elves in LOTR and the talking animals in Narnia, could interact in unique ways during this conflict.
One idea could be Sesshomaru arriving in Middle - earth in search of a powerful relic. He might cross paths with Aragorn and initially be seen as a threat. Another could be that he forms an alliance with the elves, as they both have an air of elegance and long - lived existence. Maybe he gets involved in the battle against Sauron, using his demonic powers in a way that surprises both friend and foe.
A cool plot could be that a new, extremely powerful mutant emerges who has the ability to control all forms of energy. This mutant's powers are so great that they start to disrupt the fabric of reality. The Avengers and the X - Men both realize that this mutant needs to be controlled or taught to manage their powers. However, different factions within both groups have different ideas on how to approach the situation. Some want to be more forceful, while others believe in a more diplomatic approach. This leads to internal conflicts within the combined group as they also battle external threats caused by the mutant's out - of - control powers.
One idea could be that Superman is somehow transported to the X - Men's universe. He teams up with the X - Men to fight a common enemy like a powerful mutant who has the ability to nullify Superman's powers on a large scale. They have to figure out how to combine their skills and powers to overcome this threat.
One idea could be that the kryptonite in Smallville starts to affect the mutants in strange ways. Maybe it suppresses or enhances their powers in unexpected manners. For example, Wolverine's healing factor could be slowed down by kryptonite exposure, leading to a real threat when he gets injured. Another plot could involve Lex Luthor getting his hands on some mutant DNA and trying to create his own super - soldiers, which would draw the attention of the X - Men. They could team up with Clark Kent to stop Luthor's evil plans.
One idea could be that the X - Men and Spiderman team up to fight a common enemy like Magneto who has joined forces with some of Spiderman's foes, such as Doctor Octopus. They'd have to combine their powers and skills to take on this powerful alliance.
One idea could be to have the characters from Narnia and LOTR meet in a magical realm that exists between their two worlds. For example, Frodo and the hobbits could encounter Aslan. Another could be a story where the One Ring somehow ends up in Narnia and the Narnians have to deal with its corrupting influence, while Aragorn and his companions come to Narnia to help. Maybe the White Witch could team up with Sauron, creating a more powerful and menacing villain for the combined forces of Narnia and Middle - earth to face.
Here's an idea. Buffy and Xander end up in Lothlórien. The elves are initially suspicious but then realize they are there to help. Buffy could use her agility and strength to assist in defending the forest. In another scenario, the Nazgûl could cross over to Buffy's Sunnydale. This would be a huge threat, and Buffy would have to use her knowledge of fighting demons along with the help of her friends and the weapons of Middle - earth (if they can get them) to defeat these powerful enemies.
One idea could be that the X - Men visit Hogwarts to teach the students about mutant powers and how to co - exist with those who are different. Another could be that Harry Potter discovers he has mutant abilities and has to navigate both the wizarding world and the world of mutants.