I'm not entirely sure who the specific main characters are without more detailed information about this 'Knoxville Horror Story'. It could be the victims and the perpetrators of the crime.
Since I don't have all the details about the 'Knoxville Horror Story', it's difficult to name the exact main characters. But generally, in such a story related to a crime, the main characters would be those directly involved. So, it would likely be the people who committed the heinous acts and those who were the unfortunate victims. There might also be some key law enforcement officers or witnesses who play important roles in the overall narrative.
The main characters in the 'Knoxville Horror Story' would most likely include the offenders who carried out the terrible deeds. These are the individuals who are responsible for the horror. Then there are the victims, whose lives were forever changed or ended by this incident. There may also be some secondary characters like neighbors who might have witnessed something strange prior to the event or the police officers who investigated the case and worked hard to bring justice. Without more context, it's hard to be more precise about who the main characters are exactly.