Well, it could involve Naruto being overlooked or ignored by the village in this fanfic. And his relationship with Fem Sasuke could start as a form of mutual understanding. Maybe they find solace in each other because of their own issues. For example, Naruto's loneliness due to being neglected and Fem Sasuke's own complex past.
The story could be really interesting. Naruto, being neglected, might have a different personality in this fanfic. He could be more withdrawn at first. Fem Sasuke, on the other hand, might be more assertive in approaching him. Their interactions could start off rocky but then gradually turn into a deep connection. They could learn from each other's strengths and weaknesses, like Naruto learning some of Fem Sasuke's calmness and Fem Sasuke learning Naruto's never - give - up attitude.
It could be because fans like to explore different relationship dynamics. The idea of Naruto, who is usually seen as a hero, having this flaw of neglecting someone like Fem Sasuke adds an interesting layer to their relationship.
One example could be a story where Naruto is so focused on becoming Hokage that he unintentionally neglects fem Sasuke. She might start to feel left out and lonely. In such a fanfiction, the author could explore her feelings of abandonment and how she tries to get Naruto's attention back.
There's a fanfiction called 'Silent Longing'. In this story, Fem Sasuke has feelings for Naruto but he is too busy chasing after power and recognition in the ninja world to pay attention to her. It shows how she copes with this neglect and her own growth in the process. Another one could be 'Abandoned Promises' which delves into how Fem Sasuke's expectations from Naruto are not met as he neglects her in their relationship.
One possible plot could be that Naruto, being neglected by the village, stumbles upon a fem symbiote. The symbiote bonds with him, sensing his loneliness and hidden power. Together, they start to train in secret. Naruto gradually learns to control the symbiote's powers, which are different from his chakra. As they grow stronger, Naruto decides to show the village what he can do with his new ally, proving that he's not someone to be neglected.
The neglect can create a lot of distance. For example, fem Sasuke might start to close herself off emotionally. She may feel that Naruto doesn't value her as much as she thought. This could lead to her being more cold and distant towards him.
In canon, Naruto is not completely neglected in the long run and Sasuke is male. In this fanfiction, Naruto being neglected for a long time would change his character development. And having Fem Sasuke instead of male Sasuke completely changes the dynamic of their relationship.
The plot could involve them starting a family. Fem Sasuke might be hesitant at first, worried about passing on her troubled family history. However, Naruto is excited and encourages her. They could have a child who has a unique combination of their powers. And then they have to protect this child from various threats, both from outside the village like rogue ninjas who might want to kidnap the child for its power, and from within the village where some might be jealous or fearful of the child's potential. This would bring them closer together as they work as a team to keep their family safe.
One possibility is that Naruto, filled with hatred, forms an unexpected bond with the female Kyuubi. Maybe the story could explore how they deal with Naruto's inner demons together. The fem Kyuubi might offer a different perspective on Naruto's struggle and help him find a way to overcome his hatred.
One possibility is that Naruto's upbringing by the kitsune gives him a different set of skills and values. He might be more in tune with nature and have a more mysterious aura. With the fem Kyuubi aspect, perhaps there could be a unique relationship where the fem Kyuubi acts as a guide or protector. It could also lead to Naruto having a different view of his own power and the power of the tailed beasts.
Perhaps Fem Sasuke in this fanfiction has a different view of the world. She might believe that Naruto is a threat to her goals or to the future of the ninja world she envisions. It could also be that she has some deep - seated emotional pain that she blames Naruto for, and that leads her to kill him.