Perhaps in a very dark and alternate Naruto universe, the power of some dark entity corrupts Naruto. This entity could twist his values and make him see his sister as an obstacle to achieving some ultimate power or goal. It could also be a situation where there's a time - travel paradox or a change in the timeline that alters Naruto's personality so drastically that he becomes capable of killing his sister.
If such a fanfiction exists, one possible reason could be a mind - control situation. Maybe an enemy uses some powerful genjutsu to make Naruto believe his sister is a threat, causing him to kill her accidentally. Another reason could be a misinformation plot where Naruto is tricked into thinking his sister has committed some unforgivable crime against the village.
Some writers might do it just for shock value. They want to create a story that stands out by being extremely controversial.
One possible reason could be to protect her. Naruto might believe that by leaving, he can draw danger away from his sister. For example, if there are powerful enemies targeting him, he doesn't want his sister to get caught in the crossfire.
One reason could be jealousy. If Naruto is getting more attention or has achieved more in the ninja world, his sister might be jealous and this could lead to her actions that hurt Naruto, either by spreading false rumors or directly confronting him in a hurtful way.
One possible motive could be jealousy. Maybe she was jealous of Naruto's growing power and popularity within the village. Another reason might be related to some dark family secret or a curse that forces her to take his life against her will.
It could be that his sister has some special abilities or talents that the family or the village values more. For example, if she has a very rare and powerful bloodline limit, everyone's attention would be drawn to her. In a ninja world, power and potential are highly regarded, so Naruto might be overlooked because his sister seems to have more of that 'special something' at first glance.
It could be that there was a prophecy related to his sister that made the family think she was more important. For example, a prophecy that she would be the key to saving the village in the future. And in their short - sighted view, they abandoned Naruto to focus all their resources on her.
One possible reason could be a sudden and extreme corruption of Naruto's character. Maybe he is influenced by some dark and powerful force that makes him turn against his friends. Another reason might be a misinterpretation of a prophecy or some kind of mind - control situation.
One possible reason could be a sense of betrayal. Maybe he discovers some long - hidden secrets about his family that make him feel they are not who he thought they were. For example, if he found out his parents had some kind of deal with the village elders that he disagreed with.
I'm not aware of any official 'Naruto kills his sister' fanfiction. This goes against the general nature of Naruto's character who values family and friends. Fanfiction that involves such extreme and out - of - character scenarios might be very rare or non - existent in the mainstream Naruto fanfic community.
One possible plotline could be that Naruto is under some sort of dark magic or mind control. Maybe an enemy has found a way to manipulate his actions and make him turn on his friends. Another could be a situation where Naruto is tricked into believing his friends are actually enemies in disguise. For example, if there was a powerful genjutsu that made him see his friends as threats to the village.