Naruto would be deeply hurt. He would probably feel a mix of anger and sadness. At first, he might try to reason with Tsunade, to find out why she betrayed him.
Naruto would likely be very confused. He has always considered Tsunade as a respected leader and friend. His first reaction could be disbelief. But as the reality sinks in, he would become determined to prove himself. He would use his strong willpower to overcome this setback. He might even try to find a way to make Tsunade see the truth on his own, without relying on others. He would hold on to his values and the bonds he has made with his other friends in the village. He wouldn't let this betrayal change who he is at his core, but it would definitely fuel his growth as a ninja.
He would probably also feel angry. After all, he has sacrificed so much for the village and for them. He might start to question his own beliefs and values. But Naruto being Naruto, he would not give up easily. He would try to prove his innocence and show them that they are wrong. He could go on a journey to find evidence or seek help from other allies who still believe in him, like Shikamaru or Kakashi.
Another way Naruto could react is by trying to avoid Tsunade. He might think he's done something wrong and is in trouble, so he'll start taking different routes, being more secretive about his activities. But as he does this, it could make Tsunade even more determined to stalk him. And eventually, when the truth comes out, there could be a big emotional moment between them, either of relief or of anger depending on how it's all handled.
He would probably be very confused at first. Naruto has always trusted Tsunade, so the betrayal would come as a huge shock.
Naruto would probably be extremely hurt. He has always considered Hinata a friend and perhaps more. Betrayal from her would be a huge blow to his trusting nature. He might initially be in denial, not wanting to believe that Hinata could do such a thing.
At first, Naruto would be shocked and confused. His world view would be shattered. But then, he would draw on his inner strength. He has overcome so many hardships before. He might feel a deep sadness, but also a sense of resolve. He would still believe in the power of love and friendship, and use that to face Kushina's betrayal. He could also use this experience to grow even stronger and more determined to prove himself and his beliefs.
After the initial shock, Naruto could become determined to prove his innocence if that was the case. He's a fighter, and he wouldn't just let this false accusation or betrayal stand. He might set out on a journey to find the truth and clear his name, all while struggling with the pain of his friends' actions.
The reaction would be one of shock. Naruto is a well - known figure in the ninja world, and many see him as a symbol of hope. His friends like Sakura and Sasuke would be devastated. Sakura, who has known Naruto for a long time, would likely be in disbelief and filled with anger towards Tsunade. Sasuke, depending on his state in the fanfic, might seek revenge.
He could also feel angry. After all, he has fought for his friends and the village. To be betrayed by someone like Sirzechs would make him want to prove his innocence. He might start training even harder to show that he is not the bad guy Sirzechs is making him out to be. And he would likely try to find evidence to clear his name.
Naruto would be extremely hurt. He's a very emotional person who values friendship deeply. He'd probably first try to understand why Yugao did it. He might be in denial at first, thinking it's some kind of misunderstanding.
Naruto would be determined to get to the bottom of it. He would not just accept the betrayal at face value. He would use his skills and the help of his friends to investigate what made Jiraiya turn against him. Naruto's ninja way is about never giving up, and this situation would be no different. He would fight against this betrayal, both physically if Jiraiya became an enemy in combat, and emotionally, trying to understand the reasons behind it all while still holding on to the hope that Jiraiya could be redeemed.