Naruto might initially be in denial. He's so used to having Sakura around and believing that they have a future together. So when she leaves for Sasuke, he might think it's just a temporary thing or that she's been influenced by something or someone. But as time passes and he realizes it's real, he would be deeply hurt. He might also start to question his own self - worth, thinking that he wasn't good enough for Sakura. And he might even try to win her back at first, but then slowly come to accept the situation and focus on his other responsibilities like being a ninja and protecting the village.
She could be heartbroken. Sakura has always loved Sasuke deeply, so his leaving for Naruto would be a huge blow to her. She might initially be in denial, not believing that Sasuke would choose Naruto over her.
In some fanfictions, Sakura may be determined to find Sasuke and bring him back. She could set out on her own journey, facing various challenges along the way, and growing both as a person and as a ninja in the process of trying to reunite with him.
The dynamic would be turned upside down. Sasuke would likely become more of an outcast or a loner, feeling rejected. Naruto would be in a difficult position, having to balance his friendship with Sasuke and his new relationship with Sakura. Sakura would be the catalyst for this change, and she would have to face the consequences of her actions, like dealing with the villagers' opinions and the potential backlash from Sasuke's supporters.
One possible reason could be her long - standing and deep - rooted love for Sasuke. Since childhood, she has had strong feelings for him. Maybe in this fanfiction, she realizes that her feelings for Sasuke are unshakable and that she can't continue to be with Naruto while having such intense feelings for another.
Sakura might be heartbroken. She's been in love with Sasuke for so long. She could initially go into denial, thinking it's just a temporary thing. Then she might get angry and vow to prove herself to Sasuke, perhaps by becoming an even stronger ninja.
She may initially be angry. Sakura is a proud and strong character. She could confront Sasuke and Ino, demanding an explanation. After that, she might decide to become even stronger, both in her ninja skills and her emotional resilience, to show Sasuke what he's missing.
Another reaction could be that Sakura tries to follow Sasuke. She believes that she can change his mind or that she can be of help to him. She might leave her own responsibilities behind for a while to chase after him, thinking that their bond is strong enough to overcome whatever is making Sasuke leave.
She might be heartbroken. Sakura could initially be in shock and then fall into a deep sadness. She may blame herself for Naruto's leaving, thinking that she could have done something differently.
One possible scenario is that Naruto would be initially shocked. He has always seen Sakura as Sasuke's love interest. But he might accept her feelings gradually. Sakura, on the other hand, would have to deal with the guilt of leaving Sasuke. Naruto could help her through this and they might start a new life together, facing the challenges of the ninja world as a couple.
One possible reason could be his strong bond with Naruto. Their relationship has been through so much, and Sasuke might realize that Naruto understands him on a deeper level than Sakura. Maybe he feels that his journey and growth are more intertwined with Naruto's, and he values that connection more in this fanfiction.