A possible plot could be centered around Sakura growing up with Itachi's influence. She could inherit some of the Uchiha's special abilities or at least be more attuned to their way of thinking. This could lead to her having a different role in the conflicts, such as being a mediator between the Hidden Leaf and the remaining Uchiha. It could also change her relationship with Naruto and Sasuke, as she now has a unique family connection that sets her apart.
The plot might involve Sakura discovering her relation to Itachi later in life. This could cause a stir in the Hidden Leaf Village. She might then try to understand the Uchiha clan better through Itachi. Itachi, on the other hand, could use this new bond to further his own plans to protect the village in some way.
One possible plot could be that Sakura, with her new family connection to Itachi, gets trained by him in secret. This would make her much more powerful and give her an edge in the ninja world. It could also lead to her being targeted by the same enemies as Itachi.
Yes, there are likely some fanfictions out there with this concept. Fanfiction often explores unique and unexpected relationships, and making Itachi Sakura's brother could lead to some interesting plot developments. For example, it could change the dynamics within the Naruto universe, with Itachi having a different kind of influence on Sakura's growth and decisions.
Well, perhaps the plot could involve Sakura being assigned as Itachi's secretary in a powerful ninja organization. At first, Itachi is cold and distant towards her, but Sakura is determined to do her job well. As time passes, they start to have mutual respect for each other's skills. Then, an external threat to the organization emerges, and Sakura and Itachi have to work together closely, which leads to a deeper understanding and maybe even the start of a romantic relationship between them.
Perhaps in the fanfiction, Sakura and Itachi are in a police force that has to deal with international ninja disputes. Sakura, with her intelligence and strong will, and Itachi, with his strategic mind, work together to prevent a full - scale war between two large ninja clans. They face many challenges along the way, including distrust from their own comrades who are skeptical of their unorthodox methods.
The plot could involve Itachi noticing Sakura's isolation within her own team at some point. He decides to adopt her in a sense, like becoming a mentor to her. Itachi could share his insights on how to deal with powerful enemies and the sacrifices one has to make for the greater good. Sakura would then grow not only in her combat skills but also in her understanding of the complex world of ninjas. She might start to see things from a different perspective, similar to Itachi's, which could cause some friction and also growth within her relationships with Naruto and Sasuke.
Well, one possibility is that Itachi has some hidden motives. Maybe he believes Sakura has knowledge about something important in the ninja world, like a secret jutsu or information about an enemy. So he kidnaps her to extract that information.
It could be a story where Itachi has some sort of ulterior motive for restraining Sakura. Maybe he's trying to protect her in a very unorthodox way. For example, he might be aware of a danger that only he can sense, and by restraining her wrists, he's ensuring she doesn't run into harm's way.
Maybe the plot focuses on how Itachi and Sakura got to the point of Sakura being pregnant. It could start with a secret relationship that they had been hiding from others. Then, when the pregnancy occurs, they have to decide whether to come clean about their relationship and face the reactions of their friends and comrades. They may also have to deal with the fact that Itachi has his own dark past and enemies, which could pose a threat to Sakura and the unborn child.
One possible plot could be that Itachi, in a world where he didn't have to carry out all the dark deeds he did in the original Naruto story, meets Sakura and is intrigued by her medical skills and strong will. He starts to want to get to know her better, which leads to a series of adventures where they team up to help the Hidden Leaf Village in some new and unexpected ways.
One possible plot could be that Sakura and Itachi travel back in time to the Uchiha massacre. Itachi, having a second chance, might try to find a different way to save the Uchiha clan while still protecting Konoha. Sakura, with her medical skills and knowledge of future events, could assist him. For example, she could help him find evidence to prove the Uchiha's innocence to the village elders, thus preventing the massacre from happening at all.
It could be about Sakura trying to understand Itachi's past better. Maybe she discovers some secrets about his time in the Akatsuki that no one else knew, and this new knowledge changes her perception of him.