Some of his other friends like Tracey might be really taken aback. He would have to re - adjust his perception of Ash. Serena, if she's in the story, might have a complex reaction. She could be envious in a way but also feel a stronger connection to Ash in his female form as they can now share more 'female - centric' experiences. And his rivals like Gary might initially make fun of him but later realize that Ash is still the same strong trainer despite the physical change.
His best friend Pikachu might be a bit confused at first but would quickly adapt as it still senses Ash's essence. Brock would probably be very surprised and might offer some comical comments or advice on how to handle the new situation. Misty could be a mix of shocked and intrigued. She might be a bit jealous of Ash's new female appearance at first, but then would support him as they are friends.
One possible plot could be that a spell or a magical artifact causes Ash to turn into a girl. Ericka might be involved in the discovery of this transformation. Ash then has to deal with the new physical form while still trying to pursue his Pokemon journey. His Pokemon might initially be confused but still recognize him. And he could face different challenges and reactions from his friends and rivals as a girl.
It could be that there's a prophecy or a mysterious force at work in Erika's garden. Ash, being his curious self, stumbles upon it and it transforms him. The fanfiction might explore how his Pokémon react to his new form. Some might be confused, while others could be protective. Ash, as a girl, would have to face challenges like different expectations in Pokémon battles and dealing with rivals who see him as an easy target now.
His friends would be very shocked at first. Misty might be a bit worried and try to find a way to turn him back quickly. Brock, on the other hand, would be more curious and start observing Ash - as - Pikachu to see how his behavior has changed. His Pokémon friends would also be confused. Pikachu himself might be both excited to have a 'Pikachu - like' friend but also a bit sad that his trainer is in this strange state.
At first, his friends would be in disbelief. But then, they would start to adapt. Dawn might see it as an opportunity to study a Pokémon from a different perspective. Gary could be both amused and intrigued, and might offer some scientific theories on how it happened. Overall, they would all be concerned for Ash's well - being and work together to either help him get back to normal or help him thrive in his new form.
There could be a group of Pokémon poachers who mistake Ash, in his new female form, for an easy target. They might try to capture his Pokémon while he's dealing with the changes in his body and abilities. Or perhaps there's a jealous trainer in Erika's gym who doesn't like the attention Ash is getting, even in his new form, and tries to sabotage his attempts to turn back.
Well, he might start to see the world from a Pokemon's perspective. For example, he could understand their communication better and form closer bonds with them. He may also face new challenges like having to adapt to living in a Pokeball or dealing with the natural instincts of his new Pokemon form.
Pikachu would probably be very curious. It might zap the lightsaber a bit to see what would happen, and then be in awe of the bright blade. It could also get a bit protective of Ash when he wields the lightsaber, as if it senses the added danger.
At first, Ash would be in shock. But then, he would likely turn his focus on finding out the truth. He's not one to give up easily. He'd start investigating what led to his betrayal. He might even go on a journey within the RWBY world to find evidence to clear his name and expose those who really are at fault. He'd still hold out hope that his former friends would see the truth and come back to his side.
Sakura might be initially shocked and a bit jealous at how cute Naruto - as - a - girl is. Sasuke would probably be confused at first but then act indifferent. Kakashi would be his usual calm self, but might crack a few jokes about Naruto's new look.
His friends' reactions would be mixed. Shikamaru would be like 'This is such a drag.' But he'd also start thinking of strategies to deal with the situation. Ino would be all about helping Naruto with his new look, like suggesting new outfits that would suit a fox girl. Choji would be more focused on making sure Naruto is still the same person inside. He'd offer Naruto his snacks to cheer him up. And Hinata would be blushing a lot, but also be very supportive, saying things like 'Naruto - kun, you look... different, but you're still you.'