Sasuke and Zoro could have some cool interactions. They are both very strong and somewhat brooding characters. Zoro might be interested in Sasuke's Sharingan and the power it holds, while Sasuke could be intrigued by Zoro's three - sword style.
Definitely Naruto and Luffy. Luffy is carefree and impulsive, while Naruto is also quite headstrong but has a strong sense of justice. Their interactions would be hilarious as they might not understand each other's worlds at first. For example, Luffy might be confused about Naruto's chakra and ninja tools, and Naruto might be shocked by Luffy's rubber body. Another interesting interaction could be between Naruto and Zoro. Zoro's serious and dedicated nature towards his swordsmanship could contrast with Naruto's more energetic and sometimes goofy nature.
The interaction between Naruto and Luffy would be really interesting. Luffy is carefree and impulsive, while Naruto is more about determination and protecting his friends. They could learn a lot from each other. For instance, Luffy could teach Naruto about having more fun in their adventures, while Naruto could show Luffy how to be more strategic in battles.
Definitely Naruto and the Little Sisters. Naruto has a soft spot for those in need, and the Little Sisters are in a very vulnerable position. He would probably be very protective of them, and the contrast between his energetic and positive personality and their rather timid and strange existence would be fascinating.
The interaction between Naruto and Rukia could be great. Naruto's exuberance and positive attitude could contrast with Rukia's more serious and stoic nature. They could bond over their loyalty to their friends. Maybe Naruto could make Rukia laugh with his silly antics, and Rukia could teach Naruto some of the more refined aspects of combat from the Soul Society.
Another interesting interaction could be between Gwen (from Ben 10) and Nami (from One Piece). Gwen's intelligence and magical abilities would contrast with Nami's skills in navigation and her love for treasure. They could exchange knowledge, with Gwen teaching Nami some basic magic spells in exchange for Nami teaching Gwen about navigation techniques across the Grand Line.
I think Luffy and Spider - Man would be really interesting. Luffy with his carefree and fearless nature, and Spider - Man with his witty remarks. They would probably get along well and have some crazy adventures together.
Zoro and Vegeta would also have a great interaction. Zoro, with his strong sense of honor and his goal of becoming the world's greatest swordsman, would be a worthy opponent for Vegeta. Vegeta would be interested in Zoro's swordsmanship and might even see him as a potential rival. They could have some intense training sessions together, sharing their knowledge of combat and power - up techniques.
Definitely Naruto and Twilight Sparkle. Twilight is all about knowledge and magic, and Naruto has his own unique ninja powers. They could have really deep conversations about how their powers work and share knowledge. Maybe Twilight could try to study Naruto's chakra system using her magic, and Naruto could be amazed at how Twilight's magic can do things like levitate objects and create spells.
I think Killer Croc and Jinbe would have a really unique interaction. Given that they are both sort of 'fish - like' in their own ways. Jinbe might be initially cautious around Killer Croc because of his more menacing appearance, but then they could bond over their shared strength and their experiences in the water - based environments of their respective worlds.
Definitely Superboy and Wolverine. Wolverine's gruff and experienced nature against Superboy's more idealistic and young hero self would make for some great dialogue and action scenes.