Perhaps they have wronged Naruto in some way in the fanfiction. They could have betrayed him, like telling his secrets to others or getting him into trouble on purpose. This would lead to Naruto developing hatred towards them.
It could also be that Naruto has been influenced by some external force in the fanfiction. For instance, an enemy might have planted false memories or ideas in his head, making him believe that his parents and sister are bad. This false perception could then fuel his hatred.
One possible reason could be a misunderstanding. Maybe some false information was spread about Kushina that made Naruto believe she had wronged him in some way. And for his sister, perhaps there was some sort of jealousy or miscommunication. For example, if his sister got more attention from their father or something similar.
It could be due to a misunderstanding. Perhaps there was an incident where his sister was involved, but Naruto misinterpreted her actions as something malicious against him. Like she might have accidentally broken something precious of his and he thought it was on purpose.
One possible reason could be jealousy. Maybe the sister is more favored by the villagers or has some special abilities that Naruto feels overshadow his own. This could lead to a sense of envy and ultimately hatred.
Maybe his sister is always favored by their parents, making Naruto feel left out and thus develop hatred.
One possible reason could be a misunderstanding. Maybe his team made a decision without consulting him, which made him feel left out and thus led to hatred. For example, if they took on a mission without him, Naruto, who values being part of the team, might feel betrayed.
One possible reason could be a misunderstanding within the family. Maybe there were secrets kept from him that made him feel betrayed. As for Konoha, perhaps he felt ostracized or not fully accepted by the village despite his efforts, which led to his hatred.
One possible reason could be that Naruto feels abandoned. His father was not around during his childhood, and he had to face a lot of hardships alone. Growing up without a father figure, he might have developed resentment.
One possible reason could be a misunderstanding. Maybe some false information was spread about Kushina that made Naruto believe she was a bad person. For example, if there were rumors that she abandoned him for some untrue reason, it might lead to his hatred.
It could be that Yugao has a connection to an enemy or a group that Naruto dislikes. This connection could make Naruto view her with suspicion and ultimately hatred. In some fanfiction scenarios, she could be unknowingly involved with a plot against Naruto or his village.