Spyro and Twilight Sparkle would be likely to interact. Twilight is very intelligent and well - versed in magic, and Spyro has his own dragon powers. They could learn from each other. For example, Twilight could study Spyro's dragon magic, and Spyro could learn about the complex magic system in Equestria from Twilight.
Applejack and the Heavy might be the first to interact. Applejack is a hard - working and practical character. The Heavy is a no - nonsense fighter. Applejack might see the Heavy and be curious about his large size and strange weapon. The Heavy, on the other hand, might be interested in Applejack's farming skills and the fresh apples she might be carrying. Their down - to - earth personalities could lead to an initial interaction.
Hulk might be an interesting one too. Sonic's speed could either annoy or amuse Hulk. If they end up on the same side, Sonic could use his speed to lead Hulk towards the enemies. And Hulk's raw strength could be something Sonic would be in awe of. They could have a really unique dynamic, like a fast - moving pest annoying a big, strong giant at first, but then they become an effective team.
Definitely Harry Potter and Finn Hudson. Harry is the hero in the wizarding world, and Finn is a key figure in the Glee club. They could bond over their leadership roles. Harry could teach Finn some magic tricks, and Finn could show Harry how to be more confident while performing in front of a large audience.
Probably Naruto and Robin. Robin is the leader - type in Young Justice, always thinking and strategizing. When Naruto shows up, Robin would be the one to approach him first, trying to figure out who he is and what his intentions are. Naruto, being friendly and curious, would be open to the interaction.
Luke Skywalker for sure. He's always open to new experiences and knowledge. His journey to understand the Force might lead him to be curious about the UFOs and their technology.
The Jedi would be very likely. Their connection to the Force gives them an open - mindedness and they are often exploring new parts of the galaxy. So when they encounter UFOs, they would be more likely to approach them with curiosity rather than immediate aggression.
Probably Ash and Iron Man. Iron Man is always curious about new things and Ash with his Pokémon would be quite an interesting sight for him. He'd likely approach Ash first to ask questions about what he is and what those strange creatures are.
It could be Percy and Black Widow. Natasha is a master of reading people, and she'd notice Percy right away. She might approach him in a more stealthy way compared to the others, trying to assess if he's a threat or an ally. And Percy, being used to danger, would be on his guard at first, but then start to trust her as she shows her good intentions.
Yang from RWBY might interact with the female characters from other Rooster Teeth shows. Yang is strong - willed and confident, and she could share her combat experiences with them. At the same time, she could learn new ways of handling different situations from these characters. For example, if she meets a character who is more strategic and less about brute force, it could be an eye - opener for her.
Probably Naruto and Tracer. Naruto is always eager to meet new people and make friends, and Tracer's curious and friendly nature would make her approach Naruto. They could start by comparing their abilities. Naruto would show off his Rasengan while Tracer might do a quick display of her blinking ability.