In the 'sans turns into a girl fanfiction', it could be that an ancient artifact causes the change. Sans as a girl might then use her new form to her advantage. For instance, she could be more persuasive in getting other characters to do things. Also, she may discover new powers or abilities that come with this new form, which could be used to protect the Underground in a different way than before.
Well, one possible plot could be that Sans somehow gets hit by a strange magic spell. As a girl, he/she might struggle to fit into the existing relationships in the Underground. For example, Papyrus might be really confused at first but then tries to be supportive. And Sans (as a girl) could also have different interactions with Frisk, like maybe a more motherly or sisterly bond.
Maybe in the fanfiction, there's a scientific experiment gone wrong. A human scientist was trying to find a way to bridge the gap between humans and monsters. Sans, being a curious skeleton, volunteered to be a part of the experiment. However, instead of just creating a connection, the experiment transforms Sans into a human. As a human, he experiences new emotions more intensely, like hunger and fatigue, which he didn't really have as a skeleton. He then uses his new human form to try and convince other humans that monsters are not to be feared.
Well, one possible plot could be that the other characters in the story are initially shocked. Papyrus might be super confused but also determined to take care of his 'baby' brother. They could go on little adventures where Papyrus has to protect Sans from various threats in the Underground while also trying to figure out how to turn him back to normal.
Well, one possible plot could be that Sans discovers a mysterious magic spell or artifact that gradually transforms him into a human. As he changes, he has to deal with new sensations like feeling pain and hunger in a more intense way. He also might struggle with how other characters in the Undertale world view him now that he's different.
Perhaps an evil mage who actually intended for the transformation to go wrong on purpose. They might want to use Sans' new female form to cause chaos in the Underground. They could be trying to manipulate Sans into doing bad things or using her to get to other important characters.
A possible plot could focus on how Tails' daily life changes. As a girl, she might have to deal with different social expectations. Her hobbies and interests could shift slightly. For example, she might be more interested in certain types of fashion or more nurturing activities. Her relationship with Amy could also change, perhaps they become closer friends as they share more 'girly' things. And Tails' mechanical skills might be seen in a new light, as she uses them in a different way to solve problems in her new form.
Well, perhaps in the fanfiction, Ash is exposed to a mysterious Pokémon's special ability that causes the transformation. As a girl, Ash discovers new aspects of himself. He might find that some Pokémon are more attracted to his new form and are more willing to be caught or trained. He could also use this new identity to his advantage in battles, like using the element of surprise against opponents who are used to facing the male Ash.
In a fanfiction where Nagisa turns into a girl, it could be part of a wish - fulfillment scenario. Nagisa secretly wished to experience life as a girl for a day, and some supernatural being grants that wish. As a girl, Nagisa has to navigate through daily life, school, and social situations. There could be humorous moments when Nagisa tries to act like a girl but still has some of the old habits from being a boy, like being too rough during sports in a girl's body.
Well, in a Todoroki turns into a girl fanfiction, perhaps there's a villain who has a transformation quirk and uses it on Todoroki as a form of psychological warfare. Todoroki, now a girl, has to find a way to reverse the effect. In the process, he/she realizes that society treats female heroes differently and has to fight against those prejudices too. Maybe he/she even uses this new form to her advantage in some battles, by using the element of surprise.
One possible plot could be that Cloud, after turning into a girl, has to adapt to a world that now views her differently. Maybe she struggles with newfound emotions and social expectations. For example, she might have been a tough warrior as a male, but as a girl, people underestimate her. She then has to prove herself all over again in battles or quests, while also dealing with her own internal confusion about her new identity.
Well, perhaps the story could start with Keith being exposed to a strange energy. This energy alters his DNA, turning him into a girl. As a girl, he finds that he's now treated differently in society. He uses this experience to understand the struggles that girls face. He might also have to adapt to physical changes like different body strength and new ways of expressing emotions.