The older generation, like Tsunade, would be horrified. They've seen Konoha through many hardships and would not want to see it destroyed. They would likely mobilize all available forces to stop Naruto and the Kyuubi. Meanwhile, Naruto's friends like Shikamaru and Choji would be in shock. They've always known Naruto as a kind - hearted and loyal friend, and this sudden turn would be very difficult for them to accept. They might initially be in denial and then try to find a way to stop Naruto without harming him.
The younger generation, like Sakura and the other ninja trainees, would be terrified. Some might be angry at Naruto and Kushina, while others might be more confused. Sakura, in particular, might feel betrayed as Naruto was her friend and teammate. But at the same time, she might wonder if there was a good reason behind their actions and struggle with her loyalty to Konoha and her feelings for Naruto.
Hinata would be heartbroken. She loves Naruto deeply and would likely try to understand his reasons. She would plead with him to change his mind, using her love for him as an argument, and maybe even offer to help him find a different solution to whatever problems he has with Konoha.
One possible plot could be that Naruto is pushed to the brink by the village's constant mistreatment. The Kyuubi, sensing Naruto's anger and despair, influences him to turn against Konoha. They could start by attacking key strategic points in the village, like the Hokage's office and the ninja academy, causing chaos and destruction.
The Uchiha clan might be divided. Some might support Sasuke's actions if they also feel betrayed by Konoha in the past, like how the Uchiha were treated before the massacre. But others might oppose it, seeing the long - term consequences of destroying the village.
Sasuke might be more understanding. Given his own experiences of leaving Konoha, he could respect Naruto's decision. However, he might also secretly plan to keep an eye on Naruto from afar to make sure he is safe.
Sasuke would likely be conflicted. On one hand, he has his own issues with Konoha, but on the other, he might be surprised that Naruto, who was always so loyal, would give up. He could try to understand Naruto's reasons or maybe even join him depending on the situation.
The villagers' reaction would be mixed. Some would be in awe of Fem Kyuubi's power and her act of saving Naruto. They would see her as a hero and start to change their views on the Kyuubi in general. However, there would also be those who are still fearful. They might think that Fem Kyuubi has some ulterior motives and be suspicious of her. Naruto's friends from his ninja team, like Shikamaru and Choji, would probably be more accepting. They would welcome Fem Kyuubi as long as she proves to be on Naruto's side and doesn't cause any trouble for the village.
One reason could be that Naruto has seen too much death and destruction in Konoha. His 'godlike' state might make him think that the only way to end all the suffering is to destroy the root cause, which is Konoha. He may believe that Konoha's system is so broken that it can't be fixed and needs to be completely eradicated.
Sakura would probably be very worried. She has always cared about Naruto deep down, so she might be constantly trying to find a way to bring him back. Kakashi, on the other hand, would likely understand Naruto's reasons to some extent. He might be sad but also respect Naruto's decision. As for Sasuke, if he is in the village at the time, he could be conflicted. He and Naruto have a complex relationship, and Naruto's leaving might make him realize how much Naruto actually means to him.
Sasuke would be devastated. He and Naruto had a complex relationship, and despite their differences, they were like brothers. His reaction might be to isolate himself at first, blaming himself for not being there to protect Naruto. Sakura would be heartbroken. She had deep feelings for Naruto, and his death would be a huge blow. She might become more determined to protect the village in his memory. Kakashi would feel like he failed as a teacher. He always saw Naruto's potential and to lose him would be a great loss for him.