She might interact as a mentor. Since Mikoto is from the Uchiha clan and has her own set of skills and knowledge, she could pass on some of that to Naruto. For instance, she could teach him about chakra control in a different way than he learns from Iruka or Kakashi.
In some fanfictions, Mikoto's interaction with child Naruto could be politically motivated. If she sees the potential in Naruto to change the village for the better, she might use her influence within the Uchiha clan to support Naruto, which could lead to a whole new dynamic between the Uzumaki and the Uchiha, and also within the village hierarchy.
Mikoto could interact with Naruto on an emotional level. Given that Naruto is an orphan and Mikoto is a mother figure in the Uchiha clan, she may recognize his need for love and support. So, she might give him hugs, cook for him, and generally be a nurturing presence in his life.
Well, it could be that Mikoto is trapped in a dangerous situation like a collapsing building or a genjutsu. Naruto, with his strong will and powerful chakra, breaks the genjutsu or rescues her from the rubble. He might sense her distress using his Sage Mode or his connection to the Nine - Tails' chakra and rush to her aid.
In fanfictions, their interaction can be complex. Dark Naruto might be initially distrustful of Mikoto, seeing her as part of the system that failed him. But Mikoto, with her kind heart, tries to reach out to him.
A gamer could interact by trying to form teams or clans in the Naruto world based on game concepts. They may look for characters with complementary skills to create the ultimate 'game - like' team. Also, they could introduce new forms of training that are inspired by game mechanics, like virtual reality - style training simulations.
In some fanfictions, Naruto may be in a battle and an angel comes to his aid. The angel could use its divine powers to protect Naruto from a powerful enemy attack. After that, Naruto would be curious about the angel and start asking questions. They could then form a bond where the angel decides to stay and help Naruto in his fight against evil in the ninja world.
In fanfiction, Naruto might be initially confused by Miku's appearance and her strange powers related to music. But he would quickly befriend her. He could ask her to perform at the Hidden Leaf Village festivals. They might also train together, with Naruto teaching Miku some basic ninja moves and Miku teaching Naruto about the power of music in combat.
In fanfiction, hypnosis can be a powerful tool to change the dynamics between Naruto and Mikoto. If Naruto is hypnotized, he might lose his ability to access his chakra or his ninja skills. He could be made to do things that are against his moral code. Mikoto, on the other hand, under hypnosis could be made to reveal Uchiha clan secrets. The hypnosis could also make her more vulnerable to attacks from enemies who want to take advantage of her weakened state.
If the Murcielago is a technological device, Naruto would interact with it by trying to figure out how it works. He might be clumsy at first, but with his determination, he would eventually learn to operate it. And he could use it in his missions, like using it to quickly transport himself or his teammates to different locations.
One interesting aspect could be a story where Mikoto takes a young Naruto under her wing. Maybe she sees the loneliness in him similar to Sasuke's and decides to offer him some motherly care. This could involve her teaching Naruto some basic Uchiha techniques in secret, which would add a unique twist to the story.
In some fanfictions, Naruto might be initially suspicious of Anbu Root. He could sense that there is something off about them. For example, he might notice that they seem to be operating in the shadows more than normal Anbu and start to investigate.
Gamabunta might interact with oil in various ways. He could accidentally slip on a pool of oil if it's used as a trap. Or he could use his size and strength to break through barriers made of oil. Maybe the oil has some magical properties and Gamabunta has to find a way to counteract its effects on him or his allies.