The ninja elders in Konoha could see it as a potential threat. They might worry that Fem Naruto leaving could expose Konoha's secrets or that she could be turned against the village by enemies. So, they would start to take measures to protect Konoha's interests. They could send out spies to keep an eye on her or try to find a way to bring her back. On the other hand, the younger generation of ninjas might be inspired by her courage to break free and seek their own paths outside of the village.
Well, initially, there would be chaos in the village. People would start to spread rumors about why Naruto left. His closest friends like Sakura and Kakashi would be devastated. They would try to figure out where he went and why. The Hokage at the time would have to make a decision. They could either try to convince Naruto to come back through peaceful means or prepare for the worst - case scenario if Naruto turned against the village. The village as a whole would have to face the fact that one of their most prominent members left, and it would have an impact on their reputation among other villages as well.
Some might be in shock. Naruto, regardless of being male or female in this fanfiction, has been a significant part of the village. People who have come to know her would be surprised that she would leave. They might start to question if there was something they could have done to prevent it.
Hinata would be heartbroken at first. Naruto is someone she deeply cares about. But she's also a strong - willed ninja. So she might start by trying to understand why Naruto left. She could look for clues in the village or talk to Naruto's friends to figure out his possible destination.
He could feel a sense of guilt. Sasuke might think that his actions or their relationship issues pushed Naruto to leave. He may then set out to find Naruto, not only to bring him back but also to resolve their long - standing issues. For example, if there were unspoken words or unresolved fights between them, Sasuke would see this as an opportunity to set things right.
At first, their relationship might be a bit rocky. They both have strong personalities and different ways of doing things. But as they face challenges together, they start to understand and respect each other more. Their bond grows stronger as they rely on each other for survival.
The villagers would likely be shocked. Naruto is a hero to many in Konoha, and Tsunade is the Hokage. Their sudden departure would cause a great deal of confusion and concern. Some might think that Konoha is in danger if two such important figures have left.
Some in the village would be sad to see them go. Naruto is a hero to many, and Hinata is also well - liked. People like Iruka would miss Naruto a great deal. But others might understand their need for a new life away from the village and support their decision.
Sasuke might be more understanding. Given his own experiences of leaving Konoha, he could respect Naruto's decision. However, he might also secretly plan to keep an eye on Naruto from afar to make sure he is safe.
Konoha would initially be in shock. Naruto is a hero to many in the village, and his sudden departure with Itachi, who was once considered a traitor, would cause a lot of unrest. The villagers might start to question the leadership of the village, wondering why Naruto left and if there was something they could have done to prevent it.
The village would also start to question how such a thing could happen. There would be investigations into whether Naruto was acting alone or if there was some greater conspiracy at play. Some might even blame the Hokage for not being able to prevent this tragedy from occurring.