There were many differences between the Vampire Diaries TV series and the novel version. The following are some of the main differences: 1. Plot: In the novel version, the story of the Vampire Diaries is more complicated and dramatic, including the emotional entanglement between Vampire Hunter D and the two vampire sisters. The TV series simplified the story to a fight between two vampires. 2. Character Image: The Vampire Diaries characters in the novel version are more three-dimensional and rich, including Vampire Hunter D, Mia, E-mask, Wolf, and Colonel, one of the founders of the Vampire Diaries. On the other hand, the TV series mainly retained the main characters in the novel, but the images of other characters might change. 3. Setting: The setting in the novel version is more realistic and gorgeous, including the night view of the city, the castle and the garden. On the other hand, the TV series was more compact and fast-paced, and the setting was more modern and compact. 4. Actor's performance: The performance of the actors in the novel version and the TV series version is also different. In the novel, the actors 'performance was more delicate and in-depth, which could better show the inner world of the characters. On the other hand, the TV series focused more on fast-paced narration and action scenes. There are many differences between the Vampire Diaries TV series and the novel version, but both are excellent literary works that are worthy of readers and audiences 'appreciation.