In League of Legends, if you want to send a message to your friends in the game, you can do it in the following ways: 1. Open the chat interface: You can open the chat interface by clicking the chat button on the interface or using the shortcut key "Shift + Q". 2. Add a friend: In the chat interface, click the "+" button in the friend list and enter the friend's ID or enter the friend's ID in the game to add a friend. 3. Send a message: click on the message input box and enter the message you want to send. Finally, click the "Send" button. It is important to note that sending messages in the game may cause delays due to network problems, so it is best to check the network status before sending messages.