The plot of how Professor Moriarty died in the complete Sherlock Holmes series was not developed strictly according to the original work because the original work did not explicitly mention Professor Moriarty's death. Professor Moriarty appeared as the villain in Sherlock Holmes. He was a mathematician who was dedicated to the study of criminal psychology and solving various criminal cases. His behavior aroused Holmes 'disgust and vigilance, but in the end, he was defeated by Holmes. At the end of the original novel, Professor Moriarty was stabbed in the chest by Holmes with a dagger. Holmes used the mathematical manuscript left by Professor Moriarty to answer Professor Moriarty's questions, and then Professor Moriarty died. However, in later television dramas and movies, the plot of Professor Moriarty's death was adapted, in which he was not stabbed in the chest by a dagger but died of some medical reasons.