According to the story of Pandora's Box, Pandora was created by the gods and given many gifts—beauty, wisdom, and curiosity, among others.
Favoured as she was, the king of the gods personally gave her a beautiful box as a wedding gift, but warned her that she must never open it.
Unfortunately, curiosity just happened to be one of the other 'gifts' the gods had bestowed on her.
Unable to stay away, Pandora opened the box and released disease, despair, pain and countless other misfortunes to plague humanity.
Horrified by what she had unleashed, Pandora quickly closed the box, but it was too late—the world was forever changed.
However, as she closed the lid, one last entity remained inside: hope.
Looking around the relic, Kain couldn't help but recall the story of Pandora's box and the parallels it had with his current situation.