structure based drug design success stories

American success master

Having traveled to America in the year 1862, this was the beginning of a dream, the finest of times. What constitutes a true master of success? Having some notable descendants hardly counts for anything. To build an Oil Empire alongside Rockefeller To place Carnegie on the throne of the steel magnate To help Ford propel the industrialization of automobiles worldwide To lead Edison to monopolize the future of the electrical industry To be an Angel Investor for Morgan's capital Hear this, applause!

After the autumn wood · History

Armor-Piercing Munition: Face Me, Carbon-Based Monster!

A seemingly ordinary training exercise led Chen Jian and his squad into a completely different time and space. In the post-apocalyptic world, monsters run rampant, and the surviving humans struggle to live under their terrifying claws. To fight the monsters, the living have abandoned everything. Human nature no longer exists; beastliness is the mainstream. To defeat them, one must first become them. ----------------- Chen Jian was supposed to be like the others here, pursuing the maddening evolution. But, when the tungsten-core armor-piercing round first penetrated the Kui Niu's keratin armor, he suddenly discovered... Perhaps there is another way to stay alive?

Dudu Snowball is coming · Sci-fi

Worldwide Beasttaming: I Can Design Evolution Lines

# MONSTERPET Mu Xuan transmigrated to a dangerous world of beast tamers. Fortunately, after he successfully formed a contract with a beast, he awakened two major cheats consecutively: bloodline extraction and merging as well as an information panel. Hence, Mu Xuan extracted bloodlines and designed the strongest beast evolution lines until he became the strongest beast tamer. The world was beneath his feet and the sky was not that far out of reach! Icy Crystal Spirit evolved into Icy Crystal Frost Polar Dragon, and then Cinder Frost Dragon and finally Ember Star Dragon. Space Tanuki evolved into Void Dragon Tanuki, and then Dimension Leaping Dragon Tanuki and finally Heaven Divine Dragon Tanuki. Heavenly Fate Illusion Butterfly… Nine Lives Reincarnation Butterfly. Destruction Demon Bear… Divine Elf Envoy... Golden Sun Crow… Old Man Time…

Simple Rhythm · Sci-fi

Use Me Like A Drug (omegaverse bl)

Warning: Dark and mature themes: explicit sex, heavy angst, non-detailed abuse, trauma, violence, and intense emotional tension. Please read with caution. Choi Yujun- born into power but cursed with a 'weakness'. The only son of the Choi family is born an omega, born an embarrassment to a bloodline of strong and pure alphas. At a party, a violent attack from a mutual enemy exposed Yujun’s secret in front of his family’s sworn enemy, Hwang Jaehyun, Yujun prepares for humiliation and blackmail, offering himself to be used by the Alpha in order to protect himself from his own family Instead of the humiliation...Hwang Jaehyun does the unthinkable... The rival who is supposed to destroy him, becomes his drug, his shield, his forbidden comfort. Together they fight to bring down the people who made Yujun bleed…together they bleed in the face of betrayals, trials and "Don't you realize? I'm a Choi, I am cursed and I am sick" Yujun says with deep angish, "then use me, Yujun-ah, use me like a drug" Jaehyun response came out raw and desperate, his alpha swearing it.

Cleo_notpatra · LGBT+

Project: Success

She love but got betrayed... She love but got cheated... Her heart is whole yet heartbroken... She promise that she will gave her grandfather a life full of happiness. She promise that she will make those who left them regret! It was not revenge that urge her to live. It was happiness! Revenge? Nah. I'll kill them with success! Will Min Ju still say the same if her enemies make their move? You knew that isn't the case. Her choices will change for good or for worst... Whatever her choices may be. Qing Wu Yao will stay by her side and her family will support her behind her back. Achieving success wasn't an easy task. There are some outside force that was trying to bring her down. The jealousy of a woman. The anger of a powerful man who hold a card that might bring Min Ju to ruin. Things that was lost will came back. And things that was already there will be lost. Many things happenened that change her strategy. She planned not to raise her hand but she was force to by her enemies. At last, Min Ju never thought that she'll pull the trigger to end everything. [Disclaimer: The cover is not mine. Credits to the wonderful owner] - - - Sneek Peek: "Are you in love with me?" "What if I say yes? Would you let me enter your life?" "Prove me that you're worthy." #2 "What do you think about my granddaughter?" "She was very talented. But what I like the most about her is her smile. Everytime I look at her, I fall in love at every sight."

SEVEN · Urban

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most of the werewolf stories these days are sure cliche, but this one was a better option. the world's structure was properly described and the character design is also good just waiting for next chap

Blessed with the Moon

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Well ji nuan success to find her husband that already been drugs. But her husband surely didn't want to be released from that drug immediately just because surveillance.

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Noctev242

2023-05-12

A bit of a disappointment compared to your other stories. The quality is far below your other stories. It reads like it is a translated novel. While the grammar is good and has almost no mistakes there are times when you can see that the characters have low IQ and parts that ignore common sense. His outlook on drugs aren't based on reality and often states drug facts that are just not true.

The Shopkeeper of Konoha

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This story has great build up, progression, and design. One of the best character developments and transitions based stories, I have read in a long time.

Spending My Retirement In A Game

DiceVR · Games

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breakers

2017-10-16

The pace of the story is really good; he slowly builds his power based on his own knowledge and experience. This is especially different from many other Xianxia stories where the MC meets with some fortuitous event which catapults him straight to success. This story illustrates the capabilities of human ingenuity and hard work. The MC shows how as long as a person works hard, success is possible.

The Avalon Of Five Elements

Fang Xiang · Eastern

715 Chs

Quickly wear the dark moonlight of the villain

[New Story Begins]" Please transfer to another team." [1v1][Main drama] Shen Yi was still asleep when he heard a voice saying,"Target has been bound." As a Demon Venerable who was not afraid of anything and could not even eradicate the Heavenly Dao, he never thought that someone would specially bind him. However, he was bored with his current life anyway, so he could accompany this arrogant person to play. This binding was incredible. After a few reincarnations, not only did he lose himself, but he also lost his heart. Shen Yi said,"Little bastard, wait for me to go back. I'll kill you." [System: Lord…Lord Host, please calm down.] Shen Yi,[Hurry up and tell me, why are you binding me?] Otherwise, I… Villain: Of course…to make you fall in love with me Thousands of reincarnations, just to exchange this life for you and me 1v1, rich plot

Rock candy one year old

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The Taoist master I raised has turned evil

[Pawnshop owner who loves old wine, casual and casual x Qing Fengxing, the immortal cultivator who cares about the world.] When demons and ghosts wreaked havoc in the world, war raged everywhere, and the prosperous world began to decline…The demonic path destroyed the country, and the people in power were obsessed with the pursuit of immortality, ignoring the people of the world. -- The second time they met, Song Yue threw the Qiang wine into a dry well filled with dead people's bones. Qiang Jiu looked at the dirty and smelly human bones under his feet and then looked at his stained clothes. He immediately felt a chill. He didn't expect that a cultivator who seemed to be clean about Feng Xingyue would be so "vicious". After Qiang Jiu was rescued, he was so angry that he didn't want to see Song Yue for three days.

secular disturbance

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Dressed as a disabled male lead's heart, white moonlight

Tang Jin had accidentally obtained a novel about the female lead's rebirth in the apocalypse. The male lead of this novel was called "Let Me Love You" and was considered handsome! Strong! How tragic! Being abused physically and mentally by the female lead in the novel, and even being cuckolded? Tang Jin's heart ached and she loved him. The days passed, and the zombies escalated. The high walls of Tang Jin's house were pushed down, the iron nets were torn, and Tang Jin was killed by the zombies…She woke up from the immense pain and realized that she had actually entered the world of the book,"Let Me Love You." Tang Jin was instantly overjoyed,'Does this mean that I can snatch the male lead?' Tang Jin's eyes sparkled as she glanced at the female lead,"Your man?" Sorry, I'll take it. She was dressed as the cold and aloof school belle supporting actress in Cheng Wen, while Tang Jin was the one who cut off the peach blossoms, fought in a group fight, and protected the male lead! At the same time, she was also fighting wits and courage with the female lead of Rebirth in the entertainment industry! He wanted to take the handsome male lead away from the hands of the reborn female lead! Cut off any plot that abused the male lead! <> The female protagonist (Tang Jin) who looks cold, but is a drama queen and likes to complain. X The male protagonist (Zhan Heng, also known as Shen Heng) who looks cold, but has an inferiority complex and is cold and ruthless in front of others. Demining 1: The male protagonist's legs are disabled in the early stage, but it will be easy to clear them later on. Demining 2: The world background is completely illusory and has nothing to do with reality. There is a system in the later stage. If you like it, collect more. If you don't like it, don't spray it. Thank you.

Peaches and plums

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The wife of a bad husband is still living today

Mu Yunqin had transmigrated into the book and became the 200-pound wife of the villain. According to the plot, she would be caught in a " sack of love " and thrown to the wolves after the perverted villain became famous. She would die without a complete corpse. In order to avoid a tragic ending, Mu Yunqin could only hold herself to the standards of a good wife and mother, trying to use the light of the righteous path to influence the villains. A top-notch parent-in-law with a twisted worldview? It didn't matter. She would use her blood to teach them what freedom, equality, justice, and the rule of law were! Being mocked as an ugly fat woman? It doesn't matter. I'll let you see what it means to be charming and charming. A beauty who can make people go numb with just a glance. Was his family so poor? It didn't matter. Let's see how she would earn a lot of money from women's perfume and makeup and become the richest woman in the local area. However, just as the villain was about to become famous and Mu Yunqin wanted to leave unscathed, why did the villain not have a deep relationship with the female lead and instead cling onto her? Many years later, when Yama saw his wife, who had " died tragically ", reappear in front of him and play around with women under his nose, endless dark clouds surged in his eyes. That night, the villain pinched her fair chin and used the most intimate gesture to say the most sinister words.

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The Business Guide to Time Travel

Happy, the female protagonist left on the road of sand carving and never returned… Bai Xiaonuan's life motto was,'Life is still the same, dream of becoming rich!' --------- Bai Xiaonuan looked at Little Fifth and argued,"Originally…" Cough, I just wanted to dawdle, but after meeting you, I started to get cocky!" " Where's Lian?" Little Wu was furious. He started writing on the paper. Bai Xiaonuan glanced at the four crooked letters on the paper." Tsk," she said, a little melancholic." A fish that slipped through the net of nine years of compulsory education." Little Fifth was speechless. Ahhhh, I really want to beat this guy to death! ---------

Ran Xiyan

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