Tigra vs Cheetah: A literal cat fight, this would be a matchup between hero and villain. It turns out that both of these ladies have superhuman strength, speed, stamina, agility, reflexes, and resistance to physical injury. At first I thought that this would be a one-sided fight with Cheetah as the victor, but I was surprised when I found out that Tigra's physiology enables her to heal much faster and more extensively than an ordinary human (in other words, a healing factor) while Cheetah can't. As far as I can tell, It would seem that Cheetah would have the advantage in terms of speed (she had help from Professor Zoom/Eobard Thawne to increase her speed). So which would be the deciding factor, speed or healing factor? In my opinion, probably speed.
Bloodrayne vs Blade: Both are human/vampire hybrids with different upbringings and diverse weaponry. These two have their ways of killing blood suckers through knowledge and vampire-killing weaponry. Who'd win? It could go either way. On a side note, this could as a great crossover story with both characters either ending up together as a couple or just as allies.