Ryu retracted his palm and rotated his shoulder a bit. The only real drawback was clearly the backlash. If his body wasn't strong enough to handle the increase in strength, then he would obviously suffer for it, much like a mortal smashing a fist against a concrete wall.
However, Ryu wasn't too worried about this. If he was in a situation where he needed to make use of such strength, he would be beyond needing to worry about such minor injuries. In addition, he had many methods of reinforcing his body that he hadn't used just now, and even if he didn't, with his current healing factor, dealing with such a minor ache didn't even take a single second.