Agatha (29)
A villainess would never stop targeting the leads, at least not of her own volition. And even if she was in the darkest period of her life, she would still be able to come up with ways to torment the protagonists.
Since the third day Agatha fell ill and realized she would have to stop attending tea parties and balls, she had the ministers and officers from her allied aristocratic families begin giving troubles to the Duke.
It was not simply limited to the court. The duke was also getting troubled by sudden business and territorial disputes that none of his subordinates could deal with anymore. He had to personally step up, frequently frowning after realizing that he had been targeted.