Willow Bittermane is a beautiful and aloof cafe owner in a small, semi-remote village in northern Montana. She and the female members of her family are shapeshifters, turning into wolves when the need arises. The town has legends of these “women who run with wolves” but most believe they are just stories. Willow’s life changes when she meets Garin, a handsome man who seems to despise her from their first meeting. He has an irresistible scent, though she is horrified to discover that he is a descendant of the Red Hoods, a family that has hunted her kind for generations. Despite these differences, the two are drawn together and with each other, they fight against the years of blood between their families.