Sometimes the unusual becomes the most popular, such is the case for the Teenage Mutant Ninja Turtles.
1. Roving Turtles (TMNT meets Road Rovers): General Parvo reluctantly works with the Shredder and the Foot Clan as they combine technologies to create mutated soldiers. The turtles and rovers team up to take down their enemies in New York.
Both deal with anthropomorphic animals and do have a fanbase, one more popular than the other. I believe there might be some comedy built up between the two teams and it would be interesting what the Ooze would do to Parvo. All it takes is a little bit of creative writing and you got yourself a fun crossover. Maybe not the most logical but it be fun to do.